Effervescent composition for forming a gelled composition, tablet for forming a gelled composition, and method of making a gelled composition
A method of making a gelled composition that includes combining water and an effervescent tablet in a vessel, the effervescent tablet including at least 200 mg gelatin and an effervescent couple that includes an acid and a base, heating an aqueous composition (e.g., in a microwave oven), optionally adding cold water to the heated composition, and chilling the composition for a period sufficient for the composition to form a gel.
1. An effervescent composition comprising:
from about 10% by weight to about 30% by weight of an effervescent couple comprising an acid and a base;
from at least 5% by weight to about 20% by weight of the acid;
from at least 1% by weight to about 15% by weight of the base; and
at least 200 mg of a gelatin that forms a gel, the gelatin comprising gelatin derived from a cow, gelatin derived from a pig, or a mixture thereof,
the effervescent composition forming a gel when the effervescent composition is dissolved in heated water to form an aqueous composition and the aqueous composition is subsequently chilled.
2. The effervescent composition of claim 1 comprising from about 10% by weight to about 20% by weight of the acid and from at least 5% by weight to about 15% by weight of the base.
3. An effervescent tablet comprising the effervescent composition of claim 1 , comprising at least 30% by weight of the gelatin, and further comprising
from about 5% by weight to about 40% by weight binder; and
from about 0.5% by weight to about 1% by weight lubricant.
4. The effervescent tablet of claim 3 comprising at least about 1000 mg of the gelatin.
5. The effervescent tablet of claim 3 comprising at least about 1500 mg of the gelatin.
6. The effervescent tablet of claim 3 having a hardness of at least 3 Kp.
7. The effervescent tablet of claim 3 further comprising a sweetening agent and a color agent.
8. The composition of claim 1 , wherein the composition is a uniform mixture.
9. The composition of claim 1 , wherein the composition is the form of a free flowing particulate or a tablet.
10. The composition of claim 1 , wherein the gelatin comprises gelatin derived from a pig.
11. A packaged dosage form comprising:
a sealed package; and
from about 1 gram to about 6 grams of a free-flowing particulate disposed in the sealed package, the free-flowing particulate comprising the effervescent composition of claim 1 , at least 1000 mg of a gelatin that forms a gel and a medicament.
12. A method of making a gelled composition, the method comprising:
combining the effervescent composition of claim 1 and water in a vessel to form an aqueous composition;
heating the aqueous composition in a microwave oven, the effervescent composition at least partially dissolving during the heating; and
chilling the aqueous composition for a period sufficient for the aqueous composition to form a gel.
13. The method of claim 12 , wherein the chilling occurs in an environment having a temperature of no greater than 8° C.
14. The method of claim 12 , wherein the composition forms a set gel in less than two hours when chilled at a temperature of from about 0° C. to about 8° C.
15. The method of claim 12 further comprising adding cold water having a temperature of from about 0° C. to about 25° C. to the heated aqueous composition.
16. The method of claim 12 , wherein the gel is a set gel.
17. The method of claim 12 , wherein combining the water and the effervescent tablet comprises placing from about 1 ounce to about 3 ounces of water in the vessel.
18. The method of claim 15 , wherein adding cold water comprises adding from about 1 ounce to about 3 ounces of cold water.
19. The method of claim 12 , wherein the effervescent composition comprises at least about 400 mg of the gelatin.
20. The method of claim 19 , wherein combining the water and the effervescent composition comprises placing about 0.5 ounces of water in the vessel.
21. The method of claim 20 further comprising adding about 0.5 ounces of cold water having a temperature of from about 0° C. to about 25° C. to the heated aqueous composition.
22. The method of claim 12 , wherein the effervescent composition comprises at least about 1000 mg of the gelatin.
23. The method of claim 12 , wherein the effervescent composition comprises at least about 1500 mg of the gelatin.
24. The method of claim 12 , wherein the effervescent composition comprises from about 1000 mg to about 5000 mg of the gelatin.
25. The method of claim 12 , wherein the composition forms a set gel in no greater than two hours.
26. A method of making a gelled composition, the method comprising:
heating an aqueous composition comprising the effervescent composition of claim 1 and water, the effervescent composition at least partially dissolving during the heating; and
chilling the composition to form a set gel.
27. The method of claim 26 , wherein the heating comprises heating the aqueous composition in a microwave oven.
28. The method of claim 26 , wherein the effervescent composition comprises at least 1000 mg of the gelatin.
29. The method of claim 26 further comprising adding cold water having a temperature of no greater than 25° C. to the heated aqueous composition.
30. The method of claim 29 , wherein the adding cold water comprises adding from about 1 ounce to about 3 ounces of cold water, the cold water having a temperature of from about 0° C. to about 25° C.
31. The method of claim 29 , further comprising:
placing the effervescent composition in a vessel; and
placing from about 1 ounces to about 3 ounces of tap water in the vessel,
the adding cold water comprising adding from about 1 ounce to about 3 ounces of the cold water,
the step of chilling the aqueous composition comprising placing the heated aqueous composition in a refrigerator.
32. A method of administering an active agent to an individual, the method comprising:
making a gel according to the method of claim 12 , the effervescent tablet further comprising a medicament; and
administering the gel to an individual.
33. A method of making a gelled composition, the method comprising:
combining the effervescent composition of claim 3 and water in a vessel to form an aqueous composition;
heating the aqueous composition in a microwave oven, the tablet at least partially dissolving during the heating; and
chilling the aqueous composition for a period sufficient for the aqueous composition to form a gel.
34. The method of claim 33 , wherein the effervescent tablet further comprises a medicament.
35. A method of making a gelled composition, the method comprising:
combining
a particulate comprising the effervescent composition of claim 1 comprising at least 1000 mg of the gelatin, and medicament, and
water in a vessel to form an aqueous composition;
heating the aqueous composition in a microwave oven, the particulate at least partially dissolving during the heating; and
chilling the aqueous composition for a period sufficient for the aqueous composition to form a gel.
36. A method of making a gelled composition, the method comprising:
combining the effervescent composition of claim 1 and water to form an aqueous composition; and
allowing the effervescent composition to at least partially dissolve.
37. The method of claim 36 , wherein the combining comprises adding the effervescent composition to heated water.
38. The method of claim 36 , wherein the combining comprises adding the effervescent composition to water having a temperature of at least 70° C.
39. The method of claim 36 , wherein the combining comprises adding the effervescent composition to water having a temperature of at least 80° C.
40. The method of claim 39 further comprising chilling the aqueous composition.