IP Library › Granted Patent US 8,513,193
Granted Patent B2
US 8,513,193 · App. 13/124,002 · Granted Aug 20, 2013

Protecting and repairing cartilage and musculoskeletal soft tissues

Inventors: Randy N. Rosier (Rochester, NY); Michael J. Zuscik (North Chili, NY); Erik Sampson (Rochester, NY); Susan V. Bukata (Pittsford, NY); J. Edward Puzas (Pittsford, NY); Hani Awad (Rochester, NY)
Assignee: University of Rochester
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Quick Facts
Patent No.
US 8,513,193
App. No.
13/124,002
Granted
Aug 20, 2013
Kind
B2
Abstract

Provided herein are compositions and methods related to promoting protection or repair of articular cartilage and/or musculoskeletal soft tissue by contacting the cartilage, tissues or cellular components thereof with a parathyroid hormone/parathyroid hormone-related protein (PTH/PTHrP) receptor agonist or releasing factor.

Claims (5)

1. A method of promoting repair of articular cartilage in a subject comprising

a. selecting a human subject with injured articular cartilage; and

b. administering intermittently to the subject a parathyroid hormone/parathyroid hormone-related protein (PTH/PTHrP) receptor agonist, wherein the cartilage is injured by trauma.

2. The method of claim 1 , wherein the PTH/PTHrP receptor agonist is a peptide agonist.

3. The method of claim 2 , wherein the peptide agonist is teriparatide.

Assignments (2)
CONFIRMATORY LICENSE Recorded Nov 21, 2013
From: UNIVERSITY OF ROCHESTER
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 031693/0956 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 10, 2011
From: ROSIER, RANDY N.; ZUSCIK, MICHAEL J.; SAMPSON, ERIK; BUKATA, SUSAN V.; PUZAS, J. EDWARD; AWAD, HANI
To: UNIVERSITY OF ROCHESTER
Reel/Frame 026253/0020 →
Continuity (2)
Provisional Application 61104942 · Oct 13, 2008
Related Publication 20120021986A1 · Jan 26, 2012