Method for prongf assay for in vitro diagnosis of cancer in particular breast, thyroid or lung cancer and therapeutic use of prongf
A ProNGF inhibitor for preparing a drug, said drug being in particular useful for blocking remote dissemination and cell invasion in patients suffering from cancer, in particular breast, thyroid or lung cancer.
1 . A method for treatment of a patient suffering from cancer, comprising administering a therapeutically effective amount of a ProNGF inhibitor to said patient.
2 . The method as claimed in claim 1 , wherein the amount is effective for blocking cell migration or invasion in patients suffering from cancer.
3 . The method as claimed in claim 1 , wherein the ProNGF inhibitor is an anti-ProNGF antibody or a ProNGF receptor analog in soluble form.
4 . The method as claimed in claim 1 , wherein said ProNGF inhibitor is able to specifically penetrate into cells of interest.
5 . The method as claimed in claim 1 , wherein the ProNGF inhibitor is an siRNA of a ProNGF receptor.
6 . A method of blocking cancerous cell migration, comprising administering an effective amount of a ProNGF inhibitor to a person, thereby blocking migration of cancer cells.
7 . A pharmaceutical composition, comprising, as an active ingredient, at least one ProNGF inhibitor in combination with a pharmaceutually acceptable excipient.
8 . A pharmaceutical composition as claimed in claim 7 , wherein the ProNGF inhibitor is an anti-ProNGF antibody or a ProNGF receptor analog in soluable form.
9 . A pharmaceutical composition as claimed in claim 7 , wherein the ProNGF inhibitor is an siRNA of a ProNGF receptor.
10 . A pharmaceutical composition as claimed in claim 7 , wherein said ProNGF inhibitor is able to specifically penetrate into cells of interest.