Acne vulgaris treatment regimen
View Patent ↗An improved method, formulation and kit for the treatment of acne vulgaris are disclosed. The formulation is effective in inhibiting or killing the Proprionibacterium microorganism without utilizing antibiotics A preferred formulation alleviates the four pathogenic factors involved in the development of acne a) the putative pathogen of acne, Proprionibacterium acnes , b) abnormal desquamation of sebaceous-follicle epithelium (comedogenesis), c) the androgen-induced excessive sebum production, and d) the follicular reactivity (inflammation). The formulations are preferably applied as a cream, lotion or an emulsion.
1. A method for treating acne in a patient in need thereof consisting essentially of applying therapeutically effective amounts of zinc pyrithione, linoleic acid, and a substance selected from the group consisting of propyl gallate, n-octyl gallate, n-dodecyl gallate, and combinations thereof, to said patient's skin.
2. The method of claim 1 , wherein said therapeutically effective amount of zinc pyrithione is from about 1.0% to about 2.5%.
3. A method for treating acne in a patient in need thereof consisting essentially of applying therapeutically effective amounts of zinc pyrithione, linoleic acid, a substance selected from the group consisting of propyl gallate, n-octyl gallate, n-dodecyl gallate, and combinations thereof, and a substance selected from the group consisting of salicylic acid, retinaldehyde, and combinations thereof, to said patient's skin.
4. A method for treating acne in a patient in need thereof consisting essentially of applying therapeutically effective amounts of zinc pyrithione, linoleic acid, a substance selected from the group consisting of propyl gallate, n-octyl gallate, n-dodecyl gallate, and combinations thereof, and a substance selected from the group consisting of gamma-linolenic acid, alpha-linolenic acid, cis 4,7,10,13,16,19-docosahexaenoic acid, cis-6,9,12,15-octatetraenoic acid, palmitoleic acid, oleic acid, myristoleic acid, pyridoxine hydrochloride, azelaic acid, green tea extract, arachidonic acid, and combinations thereof, to said patient's skin.
5. A method for treating acne in a patient in need thereof consisting essentially of applying therapeutically effective amounts of zinc pyrithione, linoleic acid, a substance selected from the group consisting of propyl gallate, n-octyl gallate, n-dodecyl gallate, and combinations thereof, and a substance selected from the group consisting of ethyl laurate, ethyl linoleate, beta-sitosterol and combinations thereof, to said patient's skin.
6. A method for treating acne in a patient in need thereof consisting essentially of applying therapeutically effective amounts of zinc pyrithione, linoleic acid, a substance selected from the group consisting of propyl gallate, n-octyl gallate, n-dodecyl gallate, and combinations thereof, and a substance selected from the group consisting of Vitamin E, nordihydroguaiaretic acid, dexpanthenol, and combinations thereof, to said patient's skin.
7. A method for treating acne in a patient in need thereof consisting essentially of applying therapeutically effective amounts of zinc pyrithione, linoleic acid, a substance selected from the group consisting of propyl gallate, n-octyl gallate, n-dodecyl gallate, and combinations thereof, and glycyrrhetinic acid, to said patient's skin.