IP Library Granted Patent US 8,614,343
Granted Patent B2
US 8,614,343 · App. 13/148,072 · Granted Dec 24, 2013

Process for the production of a fatty acid/carnitine derivative

Inventor: Donya Smida (La Marsa, TN)
Assignee: Lonza Ltd.
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Quick Facts
Patent No.
US 8,614,343
App. No.
13/148,072
Granted
Dec 24, 2013
Kind
B2
Abstract

The present invention discloses a process for the production of a fatty acid/L-carnitine derivative, whereby the educts are reacted in the presence of monochloroacetic acid.

Claims (7)

1. A process for the production of a fatty acid/L-carnitine hydrochloride derivative, whereby the educts are reacted in the presence of monochloroacetic acid.

2. The process according to claim 1 , whereby the educts are the chloride of a fatty acid and L-carnitine.

3. The process according to claim 1 , whereby the fatty acid is selected from the group consisting of palmitic acid, lauric acid and octanoic acid.

4. The process according to claim 1 , whereby the monochloroacetic acid is used in a concentration of between 3.3 and 4.4 mol/L, preferably in a concentration of between 3.5 and 4.3 mol/L.

5. The process according to claim 1 , whereby the chloride of the fatty acid is used in a concentration of between 1.25 and 1.85 mol/L, preferably in a concentration of between 1.6 and 1.85 mol/L.

6. The process according to claim 1 , whereby L-carnitine is used in a concentration of between 1.2 and 1.5 mol/L, preferably in a concentration of between 1.2 and 1.4 mol/L.

7. The process according to claim 1 , whereby the reaction takes place at a temperature of between 70 and 80° C.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 18, 2026
From: LONZA LTD, ALSO KNOWN AS LONZA AG
To: CAPSUGEL SWITZERLAND AG
Reel/Frame 073827/0097 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 21, 2011
From: SMIDA, DONYA
To: LONZA LTD.
Reel/Frame 026943/0580 →
Priority Claims (1)
EP 09001609 · Feb 5, 2009 · regional
Continuity (2)
Provisional Application 61150095 · Feb 5, 2009
Related Publication 20110295026A1 · Dec 1, 2011