Granted Patent
B2
US 8,802,687 · App. 13/148,579 · Granted Aug 12, 2014
Cadherin-11 inhibitors and methods of use thereof
Inventors:
Stephen W. Byers (Tacoma Park, MD); Sivanesan Dakshanamurthy (Herndon, VA); Jaime M. Guidry Auvil (Elkridge, MD); Milton L. Brown (Brookeville, MD)
Assignee:
Georgetown University
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Abstract
Cadherin-11 inhibitors, including 4-(2-phenylpyridin-3-yl)phenol, and methods for the prevention and treatment of cadherin-11 related diseases are described herein. Cadherin-11 related diseases include cancer and rheumatoid arthritis.
Claims (4)
1. A compound of the following formula:
or a pharmaceutically acceptable salt thereof.
2. A pharmaceutical composition comprising a compound of claim 1 and a pharmaceutically acceptable carrier.
3. A method of inhibiting cadherin-11 activity in a subject, comprising administering to the subject an effective amount of a compound of claim 1 .
Assignments (2)
CONFIRMATORY LICENSE
Recorded Apr 19, 2016
From: GEORGETOWN UNIVERSITY
To: US ARMY, SECRETARY OF THE ARMY
Reel/Frame 038459/0750 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 10, 2011
From: BYERS, STEPHEN W.; DAKSHANAMURTHY, SIVANESAN; GUIDRY AUVIL, JAIME M.; BROWN, MILTON L.
To: GEORGETOWN UNIVERSITY, A CONGRESSIONALLY CHARTERED INSTITUTION OF HIGHER EDUCATION
Reel/Frame 026725/0696 →
Continuity (2)
Provisional Application
61151038
· Feb 9, 2009