Antiseptic based on bispyridinium alkanes
An antimicrobially effective composition includes a) at least 0.15% by weight of bispyridinium alkane, b) at least 3.5% by weight of humectant and c) water. Upon dilution with water, the composition produces a solution with an osmolality of from 230 to 350 mOsmol/kg and is free from surfactant. It is used as an antiseptic and is suitable for use in a method for the disinfection of injured or uninjured skin of a human being or animal, preference being given to use in the case of newborns, in particular those born prematurely.
1. An antimicrobially effective composition comprising for 100% by weight:
a) between 0.15% and 5% by weight of bispyridinium alkane,
b) between 5% and 20% by weight of humectant and
c) Water,
where the composition:
is free from surfactant and wherein the composition is free of aliphatic alcohol and aromatic alcohol.
2. The composition according to claim 1 , wherein the composition is free from inorganic salts.
3. The composition according to claim 1 , wherein the composition is free from antioxidant.
4. The composition according to claim 1 , wherein component a) is octenidine dihydrochloride.
5. The composition according to claim 1 , wherein the composition comprises 0.2 to 2.5% by weight of component a).
6. The composition according to claim 1 , wherein the humectant is selected from the group of polyhydric alcohols selected from the group consisting of glycerol, 1,2-propylene glycol, sorbitol, glucose, fructose, glucuronic acid, lactose, lactic acid, lactates, lactulose, polyethylene glycols, sucrose, hyaluronic acid, xylitol, xylose and mixtures thereof.
7. The composition according to claim 6 , wherein component b) is glycerol.
8. The composition according to claim 1 , wherein the composition comprises 10 to 15% by weight of component b).
9. The composition according to claim 1 , wherein the composition consists of the components:
a) Octenidine dihydrochloride in an amount of from 0.25 to 1% by weight,
b) Glycerol in an amount of from 11 to 13% by weight, and
c) Water as the remainder.
10. A method for the disinfection of injured or uninjured skin of a human being or animal, which comprises applying to the skin an effective amount of a solution comprising, for 100% by weight:
a) 0.001% to 1% by weight of bispyridinium alkane,
b) between 5% to 20% by weight of humectants, and
c) water,
where the solution:
(i) has an osmolality of from 230 to 350 mOsmol/kg and
(ii) is free from surfactant and wherein the composition is free of aliphatic alcohol and aromatic alcohol.
11. The method according to claim 10 , characterized in that the disinfection method involves an ultrasound-associated wound treatment (UAW).
12. The method according to claim 10 , wherein the injured or uninjured skin is that of a newborn human being or animal.
13. The method according to claim 10 , wherein the injured or uninjured skin is that of a premature human being or animal.