IP Library › Granted Patent US 8,309,691
Granted Patent B2
US 8,309,691 · App. 13/188,621 · Granted Nov 13, 2012

Chlamydomonas intraflagellar transport 88 (IFT-88)

Assignees: University of Massachusetts; Yale University
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Quick Facts
Patent No.
US 8,309,691
App. No.
13/188,621
Granted
Nov 13, 2012
Kind
B2
Abstract

The invention relates to various intraflagellar transport (IFT) polypeptides and the nucleic acids that encode them. The new IFT particle polypeptides and nucleic acids can be used in a variety of diagnostic, screening, and therapeutic methods.

Claims (9)

1. An isolated antibody that binds specifically to a polypeptide consisting of the amino acid sequence of SEQ ID NO:16.

2. The antibody of claim 1 , wherein the antibody is a monoclonal antibody.

3. The antibody of claim 1 , wherein the antibody is a polyclonal antibody.

4. The antibody of claim 1 , wherein the antibody is a chimeric antibody.

5. The antibody of claim 1 , wherein the antibody is a humanized antibody.

6. The antibody of claim 1 , wherein the antibody is a single chain antibody.

7. The antibody of claim 1 , wherein the antibody is an antibody fragment.

8. The antibody of claim 7 , wherein the antibody is a Fab fragment.

9. The antibody of claim 7 , wherein the antibody is a F(ab′) 2 fragment.

Assignments (4)
CONFIRMATORY LICENSE Recorded Nov 27, 2012
From: UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 029355/0984 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 16, 2011
From: WITMAN, GEORGE B.; PAZOUR, GREGORY J.; ROSENBAUM, JOEL L.; COLE, DOUGLAS G.
To: UNIVERSITY OF MASSACHUSETTS
Reel/Frame 026758/0979 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 16, 2011
From: UNIVERSITY OF MASSACHUSETTS
To: UNIVERSITY OF MASSACHUSETTS; YALE UNIVERSITY
Reel/Frame 026759/0338 →
CONFIRMATORY LICENSE Recorded Aug 9, 2011
From: UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 026718/0623 →
Continuity (5)
Division 12481536 · Jun 9, 2009
Division 10839016 · May 5, 2004
Continuation 09866582 · May 24, 2001
Provisional Application 60206923 · May 24, 2000
Related Publication 20120046448A1 · Feb 23, 2012