IP Library Granted Patent US 9,007,061
Granted Patent B2
US 9,007,061 · App. 13/279,686 · Granted Apr 14, 2015

Method for magnetic resonance imaging using inversion recovery with on-resonant water suppression including MRI systems and software embodying same

Inventors: Matthias Stuber (Ellicott City, MD); Wesley D. Gilson (Pasadena, MD); Dara L. Kraitchman (Oxford, MD)
Assignee: The Johns Hopkins University
G01R33/4828
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Quick Facts
Patent No.
US 9,007,061
App. No.
13/279,686
Granted
Apr 14, 2015
Kind
B2
Abstract

Featured are methods for magnetic resonance imaging of a volume, such a volume having susceptibility-generating objects or interfaces having susceptibility mismatches therein. Such a method includes selectively visualizing one of susceptibility-generating objects or interfaces having susceptibility mismatches as hyperintense signals, where such visualizing includes controlling variable imaging parameters so as to control a geometric extent of a signal enhancing effect, m more particular aspects of the present invention, such selectively visualizing includes attenuating or essentially suppressing signals from fat and/or water, namely on-resonant water protons, so as to thereby enhance a signal(s) associated with magnetic susceptibility gradient(s). Also featured are MRI systems, apparatuses and/or applications programs for execution on a computer system controlling the MRI data acquisition process embodying such methods.

Claims (12)

1. A method for magnetic resonance imaging of a volume, such a volume having therein one of magnetic susceptibility-generating objects or interfaces having susceptibility mismatches; said method comprising the step(s) of:

selectively visualizing, using a magnetic resonance imaging process, the susceptibility-generating objects or interfaces having susceptibility mismatches as hyperintense signal in a volume; and

wherein such visualizing includes attenuating or essentially suppressing a signal from one or more of fat and on-resonant water, so as to control a geometric extent of a signal enhancing effect with respect to the susceptibility-generating objects or interfaces having susceptibility mismatches.

2. The method of claim 1 , wherein said attenuating or essentially suppressing of the signal from one or more of fat and on-resonant water includes:

enhancing a signal(s) associated with magnetic susceptibility gradient(s).

3. A magnetic resonance imaging (MRI) system comprising:

a gradient magnetic sub-system including one or more gradient magnets and a power controller for selectively operating each of the one or more gradient magnets;

an RF transmitter sub-system, including an RF transmitter and one or more antennas operably coupled thereto;

system controller for selectively controlling each of the gradient magnetic subsystem and the RF subsystem, said controller including a microprocessor; and

an applications program for execution on the system controller, said applications program including code segments, instructions and criteria for:

controlling each of the gradient magnetic sub-system and RF subsystem so as to selectively visualize the susceptibility-generating objects or interfaces having susceptibility mismatches as hyperintense signals, where such visualizing includes attenuating or essentially suppressing a signal from one or more of fat and on-resonant water, so as to control a geometric extent of a signal enhancing effect with respect to the susceptibility-generating objects or interfaces having susceptibility mismatches.

4. The MRI system of claim 3 , wherein said attenuating or essentially suppressing of the signal from one or more of fat and on-resonant water includes code segments, instructions and criteria to enhance a signal(s) associated with magnetic susceptibility gradient(s).

Assignments (2)
CONFIRMATORY LICENSE Recorded Apr 12, 2012
From: JOHNS HOPKINS UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 028032/0107 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 26, 2011
From: STUBER, MATTHIAS; GILSON, WESLEY D.; KRAITCHMAN, DARA L.
To: THE JOHNS HOPKINS UNIVERSITY
Reel/Frame 027122/0798 →
Continuity (3)
Division 11883534
Provisional Application 60649250 · Feb 3, 2005
Related Publication 20120062227A1 · Mar 15, 2012