NMDAR BIOMARKERS FOR DIAGNOSING AND TREATING CEREBRAL ISCHEMIA
The present invention relates to methods for detecting various subunits and isoforms of NMDA receptors to help diagnose and differentiate (1) the anatomical location of NMDA receptor over-expression, and (2) ischemic conditions in the central and peripheral nervous systems.
1 - 42 . (canceled)
43 ) An isolated peptide comprising SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3 or SEQ ID NO:4, or an analog thereof.
44 ) The peptide of claim 43 linked to a diagnostic substrate or indicator reagent.
45 ) The peptide of claim 43 comprising SEQ ID NO:1.
46 ) The peptide of claim 43 comprising SEQ ID NO:2.
47 ) The peptide of claim 43 comprising SEQ ID NO:3.
48 ) The peptide of claim 43 comprising SEQ ID NO:4.
49 ) An isolated nucleic acid that encodes for a peptide comprising SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3 or SEQ ID NO:4, or an analog thereof.