IP Library › Granted Patent US 8,944,067
Granted Patent B2
US 8,944,067 · App. 13/323,049 · Granted Feb 3, 2015

Targeted delivery of magnetically tagged active agents in combination with negative pressure wound therapy

Inventors: Timothy Mark Robinson (Basingstoke, GB); Christopher Brian Locke (Bournemouth, GB)
Assignee: KCI Licensing, Inc.
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Quick Facts
Patent No.
US 8,944,067
App. No.
13/323,049
Granted
Feb 3, 2015
Kind
B2
Abstract

Methods and systems for treating a wound using targeted delivery of magnetically-tagged active agents in combination with negative pressure wound therapy are presented. In particular, a magnetically-active wound insert may be used to attract magnetically-tagged stem cells to a wound site to treat the wound.

Claims (16)

1. A wound-treatment method comprising:

obtaining a wound dressing comprising:

a drape adapted to be coupled to the skin adjacent a wound of a patient such that the drape covers the wound and forms a space between the drape and the wound; and

a wound insert disposed within the space; wherein the wound dressing is configured to be coupled to a negative pressure source;

introducing a magnetically-tagged therapeutic agent into the body of the patient; and

applying negative pressure to the wound dressing using the negative pressure source.

2. The method of claim 1 , where the magnetically-tagged therapeutic agent is configured to be introduced into the body of the patient via a conduit coupled to the wound dressing.

3. The method of claim 1 , where the wound insert further comprises a magnetic material.

4. The method of claim 1 , further comprising releasing negative pressure from the wound dressing.

5. The method of claim 1 , further comprising reapplying negative pressure to remove accumulated fluid from the wound site.

6. The method of claim 1 , further comprising modulating the negative pressure on the wound dressing.

7. The method of claim 1 , further comprising modulating the density of the wound insert.

8. The method of claim 1 , where the wound dressing further comprises an electromagnet configured to be coupled to a voltage source.

9. The method of claim 8 , further comprising modulating the strength of the magnetic field generated by the electromagnet.

10. The method of claim 1 , further comprising coupling an electromagnet to the drape adjacent and external to the wound.

11. The method of claim 1 , further comprising holding a magnet sufficiently close to the wound that the magnetically-tagged therapeutic agent is drawn toward the wound.

Assignments (5)
RELEASE OF SECURITY INTEREST IN PATENTS Recorded Nov 7, 2019
From: WILMINGTON TRUST, NATIONAL ASSOCIATION
To: KCI USA, INC.; KCI LICENSING, INC.
Reel/Frame 050966/0547 →
RELEASE OF SECURITY INTEREST REEL/FRAME 040098/0268 Recorded Feb 8, 2017
From: WILMINGTON TRUST
To: KCI USA, INC.
Reel/Frame 041666/0320 →
LIMITED THIRD LIEN INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Oct 7, 2016
From: KCI USA, INC.; LIFECELL CORPORATION; KCI LICENSING, INC.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 040291/0237 →
SECOND LIEN SECURITY AGREEMENT Recorded Sep 21, 2016
From: KCI USA, INC.; LIFECELL CORPORATION; KCI LICENSING, INC.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 040098/0268 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 20, 2011
From: ROBINSON, TIMOTHY MARK; LOCKE, CHRISTOPHER BRIAN
To: KCI LICENSING, INC.
Reel/Frame 027419/0734 →
Continuity (2)
Provisional Application 61423459 · Dec 15, 2010
Related Publication 20120157750A1 · Jun 21, 2012