IP Library Granted Patent US 8,695,640
Granted Patent B2
US 8,695,640 · App. 13/360,261 · Granted Apr 15, 2014

Microfabricated elastomeric valve and pump systems

Inventors: Marc A. Unger (South San Francisco, CA); Hou-Pu Chou (Pasadena, CA); Todd A. Thorsen (Pasadena, CA); Axel Scherer (Laguna Beach, CA); Stephen R. Quake (San Marino, CA)
Assignee: California Institute of Technology
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Quick Facts
Patent No.
US 8,695,640
App. No.
13/360,261
Granted
Apr 15, 2014
Kind
B2
Abstract

A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first elastomeric layer; forming a second elastomeric layer on top of a second micromachined mold, the second micromachined mold having a second raised protrusion which forms a second recess extending along a bottom surface of the second elastomeric layer; bonding the bottom surface of the second elastomeric layer onto a top surface of the first elastomeric layer such that a control channel forms in the second recess between the first and second elastomeric layers; and positioning the first elastomeric layer on top of a planar substrate such that a flow channel forms in the first recess between the first elastomeric layer and the planar substrate.

Claims (17)

1. A microfabricated elastomeric device comprising:

a base layer;

a first elastomeric layer having a top surface and a bottom surface,

wherein the bottom surface of the first elastomeric layer is bonded to the base layer;

wherein the bottom surface comprises a first recess such that the first recess and the base layer form a first flow channel,

wherein the first elastomeric layer comprises a first via extending from the bottom surface to the top surface of the first elastomeric layer and disposed within the first elastomeric layer on a first side of the first recess, and

wherein the first elastomeric layer comprises a second via extending from the bottom surface to the top surface of the first elastomeric layer and disposed within the first elastomeric layer on a second side of the first recess; and

a second elastomeric layer having a top surface and a bottom surface,

wherein the bottom surface of the second elastomeric layer is bonded to the top surface of the first elastomeric layer, and

wherein the bottom surface of the second elastomeric layer comprises a second recess such that the second recess, the top surface of the first elastomeric layer, the first via, and the second via form a second flow channel.

2. The microfabricated elastomeric device of claim 1 , wherein the first recess has a depth between 0.2 and 250 microns.

3. The microfabricated elastomeric device of claim 1 , wherein the base layer comprises a semiconductor.

4. The microfabricated elastomeric device of claim 1 , wherein at least a portion of either or both the first elastomeric layer or the second elastomeric layer is flexible.

5. The microfabricated elastomeric device of claim 1 , wherein either or both the first elastomeric layer or the second elastomeric layer are made from an elastomeric material having a Young's modulus of between about 20 Pa-1 GPa.

6. The microfabricated elastomeric device of claim 1 , wherein the first elastomeric layer and the second elastomeric layer comprise an elastomeric structure.

7. The microfabricated elastomeric device of claim 1 , wherein the base layer comprises a non-elastomer.

8. The microfabricated elastomeric device of claim 1 , wherein the base layer comprises an elastomer.

Assignments (1)
CONFIRMATORY LICENSE Recorded May 17, 2012
From: CALIFORNIA INSTITUTE OF TECHNOLOGY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 028224/0495 →
Continuity (7)
Continuation 12540994 · Aug 13, 2009
Continuation 09724967 · Nov 28, 2000
Continuation In Part 09605520 · Jun 27, 2000
Provisional Application 60141503 · Jun 28, 1999
Provisional Application 60147199 · Aug 3, 1999
Provisional Application 60186856 · Mar 3, 2000
Related Publication 20120328834A1 · Dec 27, 2012