IP Library Granted Patent US 8,604,070
Granted Patent B2
US 8,604,070 · App. 13/360,895 · Granted Dec 10, 2013

Use of inhibitors of the renin-angiotensin system

Inventors: Hugh Edward Montgomery (London, GB); John Francis Martin (London, GB); Jorge Daniel Erusalimsky (London, GB)
Assignee: FinVector Vision Therapies, Ltd.
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Quick Facts
Patent No.
US 8,604,070
App. No.
13/360,895
Granted
Dec 10, 2013
Kind
B2
Abstract

It has been found that inhibitors of the rennin-angiotensin system are useful for the treatment or prevention of conditions associated with hypoxia or impaired metabolic function or efficiency. In particular, they may be used in connection with therapy of stroke or its recurrence, the acute treatment of myocardial infarction, and the treatment or prevention of wasting or cachexia, and are thus useful in treatment of the symptoms and signs of aging. These inhibitors may also be used to enhance function in healthy subjects.

Claims (1)

1. A method for the treatment of a person, wherein said method comprises administering to a person with hypertension and left ventricular hypertrophy in need of such treatment an inhibitor of the renin-angiotensin system wherein the inhibitor is an AT I receptor antagonist and wherein said antagonist consists of losartan in an amount effective to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy.

Assignments (4)
RELEASE OF SECURITY INTEREST Recorded Jan 31, 2022
From: PHARMACEUTICAL PATENT ATTORNEYS, LLC
To: TRIZELL LTD., F/K/A FINVECTOR LTD. F/K/A ARK THERAPEUTICS LTD.
Reel/Frame 058826/0044 →
SECURITY INTEREST Recorded Nov 19, 2020
From: TRIZELL LTD.
To: PHARMACEUTICAL PATENT ATTORNEYS, LLC
Reel/Frame 054775/0546 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 5, 2014
From: FINVECTOR VISION THERAPIES LTD
To: HEALTH SCIENCE FUNDING, LLC
Reel/Frame 034108/0413 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 30, 2012
From: MONTGOMERY, HUGH EDWARD; MARTIN, JOHN FRANCIS; ERUSALIMSKY, JORGE DANIEL
To: ARK THERAPEUTICS LIMITED F/K/A EURGOGENE LIMITED
Reel/Frame 027621/0358 →
Priority Claims (2)
GB 9722026.3 · Oct 17, 1997 · national
GB 9810855.8 · May 20, 1998 · national
Continuity (7)
Division 12205090 · Sep 5, 2008
Continuation 11441648 · May 25, 2006
Continuation 10206659 · Jul 26, 2002
Continuation 09529628
Provisional Application 60067819 · Dec 5, 1997
Provisional Application 60094902 · Jul 31, 1998
Related Publication 20120178784A1 · Jul 12, 2012