Granted Patent
B2
US 9,241,928 · App. 13/379,575 · Granted Jan 26, 2016
Antimicrobial compounds
Inventors:
Terence Moy (Wayland, MA); Annie Conery (Belmont, MA); Kim Lewis (Newton, MA); Frederick M. Ausubel (Newton, MA); Read Pukkila-Worley (Cambridge, MA)
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Abstract
This disclosure relates to compositions including certain compounds identified by a quantitative, high throughput assay to be effective in inhibiting the ability of a bacterium to kill a host organism, as well as methods for using these compounds for treating bacterial infections.
Claims (3)
1. A pharmaceutical composition, comprising a pharmaceutically acceptable carrier and
2. A method of treating a bacterial infection in a subject in need thereof, comprising administering to the subject the pharmaceutical composition of claim 1 in an amount effective to treat the infection;
wherein the bacterial infection is gastro-intestinal tract infection.
Assignments (4)
CONFIRMATORY LICENSE
Recorded Dec 11, 2014
From: THE GENERAL HOSPITAL CORPORATION
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 034610/0921 →
CONFIRMATORY LICENSE
Recorded Nov 6, 2012
From: THE GENERAL HOSPITAL CORPORATION
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 029246/0912 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded May 9, 2012
From: MOY, TERENCE; CONERY, ANNIE; AUSUBEL, FREDERICK M.; PUKKILA-WORLEY, READ
To: THE GENERAL HOSPITAL CORPORATION
Reel/Frame 028181/0717 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded May 9, 2012
From: LEWIS, KIM
To: NORTHEASTERN UNIVERSITY
Reel/Frame 028181/0788 →
Continuity (2)
Provisional Application
61220842
· Jun 26, 2009