IP Library › Granted Patent US 9,295,673
Granted Patent B2
US 9,295,673 · App. 13/403,856 · Granted Mar 29, 2016

Combination of mTOR inhibitors and P13-kinase inhibitors, and uses thereof

Inventors: Pingda Ren (San Diego, CA); Yi Liu (San Diego, CA); Katayoun Jessen (San Diego, CA); Xin Guo (San Diego, CA); Christian Rommel (La Jolla, CA); Troy Edward Wilson (San Marino, CA)
Assignee: Intellikine LLC
A61K31/551A61K31/4439A61K31/4745A61K31/498A61K31/501A61K31/517A61K31/519A61K31/527A61K31/53A61K31/5377A61K31/541A61K45/06
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 9,295,673
App. No.
13/403,856
Granted
Mar 29, 2016
Kind
B2
Abstract

The present invention provides for a method for treating a disease condition associated with PI3-kinase α and/or mTOR in a subject. In another aspect, the invention provides for a method for treating a disease condition associated with PI3-kinase α and/or mTOR in a subject. In yet another aspect, a method of inhibiting phosphorylation of both Akt (S473) and Akt (T308) in a cell is set forth.

Claims (4)

1. A method for treating breast cancer comprising administering to a subject in need thereof a therapeutically effective amount of the mTOR inhibitor:

or a pharmaceutically acceptable salt thereof; and

a therapeutically effective amount of the PI3-kinase α inhibitor:

or a pharmaceutically acceptable salt thereof.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 25, 2012
From: REN, PINGDA; LIU, YI; JESSEN, KATAYOUN; GUO, XIN; ROMMEL, CHRISTIAN; WILSON, TROY EDWARD
To: INTELLIKINE LLC
Reel/Frame 029023/0814 →
Continuity (2)
Provisional Application 61446016 · Feb 23, 2011
Related Publication 20120294930A1 · Nov 22, 2012