Selective oxidation of organic substrates to partially oxidized products
View Patent ↗Selective oxidation of organic substrates to partially oxidized products by ozone in acetonitrile solvent, using Fe(II) catalysis.
1. A method of selectively oxidizing organic substrates with weak C—H bonds, in the presence of ozone to partially oxidized products, comprising:
reacting the organic substrate and ozone in acetonitrile solvent in the presence of iron(II) catalyst.
2. The process of claim 1 wherein the organic substrate is selected from the group consisting of acetonitrile-soluble alcohols and ethers.
3. The process of claim 2 wherein the organic substrate is an alcohol.
4. The process of claim 2 wherein the organic substrate is benzyl alcohol, and the selective oxidation product benzaldehyde.
5. The process of claim 2 wherein the alcohol is methanol, and the selective oxidation product is formaldehyde.
6. The process of claim 2 wherein the organic substrate is an ether.
7. The process of claim 1 wherein the amount of catalyst is from 0.1% to 1.0% by weight of the reactants.
8. The process of claim 1 wherein the iron(II) catalyst is one which is soluble in acetonitrile.
9. The process of claim 8 wherein the iron(II) salt is selected from the group consisting of iron(II) triflate, iron II tetrafluro borate and iron(II) hexafluorophosphate.