IP Library › Patent Application 13437159
Patent Application
App. No. 13/437,159

Treatment of Dermatological Pathologies

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Quick Facts
Patent No.
US None
App. No.
13/437,159
Abstract

Skin inflammation in a human subject is reduced by administering to the subject a pharmaceutical composition that includes a pharmaceutically acceptable carrier and a therapeutically effective amount of an agent that selectively binds IL-1α.

Claims (8)

1 . A method of reducing skin inflammation in a human subject, the method comprising the step of administering to the subject a pharmaceutical composition comprising a pharmaceutically acceptable carrier and an amount of an agent that selectively binds IL-1α effective to reduce skin inflammation in the subject.

2 . The method of claim 1 , wherein the agent is an anti-IL-1α antibody.

3 . The method of claim 2 , wherein the anti-IL-1α antibody is a monoclonal antibody.

4 . The method of claim 3 , wherein the monoclonal antibody is an IgG1.

5 . The method of claim 3 , wherein the monoclonal antibody comprises a complementarity determining region of MABp1.

6 . The method of claim 3 , wherein the monoclonal antibody is MABp1.

7 . The method of claim 1 , wherein the skin inflammation is associated with acne vulgaris.

8 . The method of claim 1 , wherein the skin inflammation is associated with psoriasis vulgaris.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 10, 2020
From: XBIOTECH INC.
To: JANSSEN BIOTECH, INC.
Reel/Frame 051769/0927 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 15, 2012
From: SIMARD, JOHN
To: XBIOTECH, INC.
Reel/Frame 028208/0536 →