IP Library Granted Patent US 8,580,320
Granted Patent B2
US 8,580,320 · App. 13/443,995 · Granted Nov 12, 2013

Cosmetic preparation and method for preparing the same

Inventors: Peter Blum (Richterswil, CH); Cornelia Schurch (Lenzburg, CH); Daniel Schmid (Brugg, CH); Fred Zulli (Kuttigen, CH)
Assignee: Mibelle AG
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Quick Facts
Patent No.
US 8,580,320
App. No.
13/443,995
Granted
Nov 12, 2013
Kind
B2
Abstract

The present invention relates to the use of dedifferentiated plant cells in cosmetic preparations for protecting of stem cells against intrinsic and extrinsic stress factors, in particular for promoting proliferation of stem cells and for protecting them against apoptosis. In particular, the invention relates to the use of dedifferentiated plant cells from fruits of Malus domestica (Apple) cultivar Uttwiler Spaetlauber . Further, the invention relates to a method for cultivating of dedifferentiated plant cells, as well as to the preparation of extracts of plant cell cultures which are suitable for such applications.

Claims (11)

1. A cosmetic preparation for the treatment of skin stem cells, comprising:

a dermatologically suitable carrier suitable for exterior application to the human body; and

an active component blended with said carrier, wherein said active component comprises an effective amount of an extract obtained from high pressure homogenization of cultivated dedifferentiated plant cells in the presence of finely dispersed liposomes to encapsulate and stabilize said extract therein, wherein said dedifferentiated plant cells originate from Malus domestica cultivar Uttwiler Spaetlauber.

2. The cosmetic preparation as set forth in claim 1 , comprising 0.01 to 90 percent by weight of said active component relative to said carrier.

3. The cosmetic preparation as set forth in claim 2 , comprising 0.1 to 10 percent by weight of said active component relative to said carrier.

4. A cosmetic preparation as set forth in claim 2 , wherein said active component is provided in an effective amount to promote proliferation, protection and vitalization of said stem cells.

5. A cosmetic preparation as set forth in claim 2 , wherein said active component is provided in an effective amount to protect hair follicle stem cells.

6. The cosmetic preparation of claim 1 , wherein said finely dispersed liposomes are of size of about 50 nanometer.

7. The cosmetic preparation of claim 1 , wherein said dedifferentiated plant cells are homogenized at a pressure of about 1200 bar.

8. A cosmetic preparation as set forth in claim 1 , wherein said cosmetic preparation further comprises pharmaceutically and cosmetically compatible preservative agents and antioxidants.

9. A cosmetic preparation as set forth in claim 1 , wherein said cosmetic preparation is provided in creams, soaps, lotions, gels or hair serum.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 29, 2026
From: MIBELLE AG
To: SOLABIA BIOCHEMISTRY AG
Reel/Frame 074794/0435 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 12, 2012
From: BLUM, PETER; SCHURCH, CORNELIA; SCHMID, DANIEL; ZULLI, FRED, DR.
To: MIBELLE AG
Reel/Frame 028032/0278 →
Priority Claims (1)
CH 0701/07 · Apr 27, 2007 · national
Continuity (2)
Continuation 12148241 · Apr 17, 2008
Related Publication 20120195948A1 · Aug 2, 2012