BIOERODIBLE MATRIX FOR TISSUE INVOLVEMENT
Disclosed herein are polyurethane polymer matrices with a porosity of from about 20 microns to about 90 microns that are useful in promoting closure and protection of incision sites; supporting the lower pole position of breast implants; and providing a partial or complete covering of breast implants to provide a beneficial interface with host tissue and to reduce the potential for malpositioning or capsular contracture. The disclosed matrices can be seeded with mammalian cells.
1 . A medical implant for promoting tissue generation in a patient, the medical implant comprising a matrix including a resorbable or bioerodible polymer component and a cellular component.
2 . The medical implant of claim 1 wherein the polymer component comprises silk.
3 . The medical implant of claim 1 wherein the polymer component is a polyurethane polymer.
4 . The medical implant of claim 1 wherein the polymer component comprises a porous polyurethane polymer.
5 . The medical implant of claim 1 wherein the polymer component comprises a porous polyurethane polymer having a porosity of from about 20 microns to about 350 microns.
6 . The medical implant of claim 1 wherein the polymer component comprises polycarolactone soft segments.
7 . The medical implant of claim 1 wherein the cellular component comprises stem cells.
8 . The medical implant of claim 1 wherein the cellular component comprises adipose cells.
9 . The medical implant of claim 1 wherein the cellular component comprises stem cells and adipose cells.