IP Library Granted Patent US 9,318,228
Granted Patent B2
US 9,318,228 · App. 13/457,174 · Granted Apr 19, 2016

Production of radionuclide molybdenum 99 in a distributed and in situ fashion

Inventors: Charles A. Gentile (Plainsboro, NJ); Adam B. Cohen (Princeton Junction, NJ); George Ascione (Cream Ridge, NJ)
G21G4/02G21G1/12G21G2001/0036
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Quick Facts
Patent No.
US 9,318,228
App. No.
13/457,174
Granted
Apr 19, 2016
Kind
B2
Abstract

A method and apparatus for producing Mo-99 from Mo-100 for the use of the produced Mo-99 in a Tc-99m generator without the use of uranium is presented. Both the method and apparatus employ high energy gamma rays for the transformation of Mo-100 to Mo-99. The high energy gamma rays are produced by exposing a metal target to a moderated neutron output of between 6 MeV and 14 MeV. The resulting Mo-99 spontaneously decays into Tc-99m and can therefore be used in a Tc-99m generator.

Claims (10)

1. A method of producing Mo-99 from a Mo-100 target, the method comprising:

providing a neutron output with an average energy of between about 6MeV and about 14.1 MeV;

moderating with a moderator the neutron output to produce a moderated neutron output with an average energy range of between about 6 MeV and about 14 MeV;

exposing a copper target to the moderated neutron output to produce gamma rays of greater than 8 MeV, and

exposing the Mo-100 target to the gamma rays of greater than 8 MeV to produce Mo-99 with a yield of approximately 7.7×10 −6 microcuries per gram to 2.4×10 −3 microcuries per gram.

2. The method of claim 1 , further comprising collecting the Mo99 produced and transferring the Mo99 to a Technetium-99m generator.

3. The method of claim 1 , wherein the neutrons are produced from a deuterium-tritium (D-T) Neutron generator.

4. The method of claim 1 , wherein the moderator comprises polyethylene.

5. The method of claim 1 , wherein the molybdenum target comprise a coupon.

6. The method of claim 1 , wherein the molybdenum target comprises powdered molybdenum disposed in a fluid.

Assignments (2)
CONFIRMATORY LICENSE Recorded May 14, 2014
From: PRINCETON UNIVERSITY
To: ENERGY, UNITED STATES DEPARTMENT OF
Reel/Frame 032913/0932 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 12, 2012
From: GENTILE, CHARLES A.; COHEN, ADAM B.; ASCIONE, GEORGE
To: THE TRUSTEES OF PRINCETON UNIVERSITY
Reel/Frame 028533/0873 →
Continuity (2)
Provisional Application 61479278 · Apr 26, 2011
Related Publication 20120275557A1 · Nov 1, 2012