IP Library › Granted Patent US 8,906,387
Granted Patent B2
US 8,906,387 · App. 13/472,260 · Granted Dec 9, 2014

In vivo transduction with a chimeric AAV capsid protein

Inventors: Mark Kay (Los Altos, CA); Dirk Grimm (Palo Alto, CA)
Assignee: The Board of Trustees of the Leland Stanford Junior University
C12N15/86C12N2750/14143C07K14/005C12N2750/14122
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Quick Facts
Patent No.
US 8,906,387
App. No.
13/472,260
Granted
Dec 9, 2014
Kind
B2
Abstract

Recombinant adeno-associated viral (AAV) capsid proteins are provided. Methods for generating a library of recombinant adeno-associated viral capsid proteins are also provided.

Claims (1)

1. An isolated cell comprising: a recombinant AAV (rAAV) vector, wherein said rAAV vector comprises a DNA of interest and a capsid protein having an amino acid sequence selected from the group of sequences consisting of (i) sequences having at least 95% sequence identity over the entire length of SEQ ID NO:1 and (ii) SEQ ID NO:1.

Assignments (1)
CONFIRMATORY LICENSE Recorded May 30, 2012
From: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 028291/0898 →
Continuity (5)
Continuation 13297110 · Nov 15, 2011
Division 12538791 · Aug 10, 2009
Continuation 11731314 · Mar 30, 2007
Provisional Application 60787371 · Mar 30, 2006
Related Publication 20120255046A1 · Oct 4, 2012