Composition for solubilizing tissue and cells comprising N-tetradecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate and polyoxyethylene (10) cetyl ether

1. A composition, comprising:

N-tetradecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate; and

polyoxyethylene (10) cetyl ether.

2. The composition of claim 1 , wherein the composition has a pH more basic than about 7.0 in a buffer solution.

3. The composition of claim 1 , wherein the composition has a pH of between about 7.0 and about 9.0 in a buffer solution.

4. The composition of claim 1 , further comprising a buffer solution that dissolves the N-tetradecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate and the polyoxyethylene (10) cetyl ether, one or both of the N-tetradecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate and the polyoxyethylene (10) cetyl ether each being in an amount of about 0.25% w/v with respect to the buffer solution.

5. A method for solubilizing and remodeling and/or removing tissue on or beneath a patient's skin, the method comprising:

applying energy to a region of interest on the skin; and

contacting the region with a tissue solubilizing composition, the tissue solubilizing composition comprising:

N-tetradecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate; and

polyoxyethylene (10) cetyl ether.

6. The method of claim 5 , further comprising:

removing at least a portion of the solubilized region of interest to leave an exposed area on the skin; and

applying to the exposed area at least one of a therapeutic composition and a cosmetic composition.

7. The method of claim 6 , wherein the applying comprises applying to the exposed area a therapeutic composition comprising at least one of a DNA-based drug, an RNA-based drug, a protein-based drug, a peptide-based drug, a lipid-based drug, a carbohydrate-based drug, a small molecule drug, a nanoparticle-based drug, and a liposome-encapsulated drug.

8. The method of claim 6 , wherein the applying comprises applying to the exposed area a cosmetic composition comprising at least one of elastin, an elastin-based peptide, collagen, a collegen-based peptide, resveratrol, idebenone, co-enzyme Q10, acetyl hexapeptide-3, glycosaminoglycans, palmitoyl pentapeptide-4, sodium hyaluronate, and combinations thereof.

9. A method for recovering analytes from mucosal membrane, skin, or other tissue, the method comprising:

applying energy to a region of interest on the mucosal membrane, skin, or other tissue containing at least one analyte;

contacting the region with a tissue solubilizing composition, thereby solubilizing at least some of the mucosal membrane, skin, or other tissue containing at least one analyte,

wherein the tissue solubilizing composition comprises:

N-tetradecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate; and

polyoxyethylene (10) cetyl ether; and

collecting the at least one analyte from the solubilized mucosal membrane, skin, and other tissue.

10. The method of claim 9 , wherein the analyte comprises a protein.

11. The method of claim 9 , wherein the analyte comprises a cancer biomarker.

12. The method of claim 9 , wherein the analyte comprises an antibody.

13. The method of claim 9 , wherein the analyte comprises a peptide.

14. The method of claim 9 , wherein the analyte comprises a lipid.

15. The method of claim 9 , wherein the analyte comprises a nucleic acid.

16. The method of claim 9 , wherein the analyte comprises a small molecule.

17. The method of claim 9 , wherein the analyte comprises a microbe.

18. The method of claim 9 , wherein the analyte comprises a warfare agent.

19. The method of claim 9 , wherein the analyte comprises an environmental contaminant.

20. The method of claim 9 , wherein the analyte comprises a drug.