Granted Patent
B1
US 8,426,450 · App. 13/478,361 · Granted Apr 23, 2013
Substituted 4-phenyl pyridines having anti-emetic effect
Inventors:
Luca Fadini (Giubiasco, CH); Peter Manini (Giubiasco, CH); Claudio Pietra (Como, IT); Claudio Giuliano (Como, IT); Emanuela Lovati (Mendrisio, CH); Roberta Cannella (Varese, IT); Alessio Venturini (Varese, IT); Valentino J. Stella (Lawrence, KS)
Assignee:
Helsinn Healthcare SA
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Abstract
Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the neurokinin (NK 1 ) receptor. The compounds have the general formula (I):
Claims (5)
1. The compound:
or a pharmaceutically acceptable salt thereof.
2. A pharmaceutical composition comprising a therapeutically effective amount of a compound according to claim 1 , and one or more pharmaceutically acceptable excipients.
3. A compound selected from the group consisting of:
or a pharmaceutically acceptable salt thereof.
Assignments (3)
RELEASE OF SECURITY INTEREST
Recorded Sep 20, 2023
From: HAMILTON SA LLC
To: HELSINN HEALTHCARE SA; HELSINN THERAPEUTICS (U.S.), INC.; HELSINN BIREX PHARMACEUTICALS LIMITED
Reel/Frame 064961/0567 →
SECURITY INTEREST
Recorded Dec 30, 2022
From: HELSINN HEALTHCARE SA; HELSINN THERAPEUTICS (U.S.), INC.; HELSINN BIREX PHARMACEUTICALS LIMITED
To: HAMILTON SA LLC
Reel/Frame 062254/0888 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Nov 28, 2012
From: FADINI, LUCA; MANINI, PETER; PIETRA, CLAUDIO; GIULIANO, CLAUDIO; LOVATI, EMANUELA; CANNELLA, ROBERTA; VENTURINI, ALESSIO; STELLA, VALENTINO J.; BRAGLIA, RICCARDO
To: HELSINN HEALTHCARE SA
Reel/Frame 029365/0544 →
Continuity (1)
Provisional Application
61564537
· Nov 29, 2011