Synergistic combinations of polyene fungicides and non-ribosomal peptides and related methods of use
The present invention includes compositions comprising a synergistic fungicidal combination of a polyene fungicide and at least one lipopeptide and methods for using such compositions in controlling fungal pathogens.
1. A composition comprising a synergistic fungicidal combination of a polyene fungicide and at least one lipopeptide, wherein the polyene fungicide is natamycin and the at least one lipopeptide comprises one or more fengycin-type compounds and one or more iturin-type compounds and wherein the weight to weight ratio of the polyene fungicide and the at least one lipopeptide is about 1:1.
2. The composition of Claim 1 further comprising one or more surfactin-type compounds.
3. The composition of claim 1 wherein the at least one lipopeptide is part of or an extract of a fungicidal lipopeptide-containing fermentation product.
4. The composition of claim 3 wherein the lipopeptide-containing fermentation product is from a Bacillus species bacteria.
5. The composition of claim 4 wherein the Bacillus species bacteria is selected from the group consisting of Bacillus subtilis and Bacillus amyloliquefaciens.
6. The composition of claim 4 wherein the Bacillus subtilis is selected from the group consisting of Bacillus subtilis QST713 and its variants.
7. A method for controlling fungal phytopathogens comprising applying to a plant, root, seed or soil surrounding the plant an effective amount of a composition comprising a synergistic fungicidal combination of a polyene fungicide and at least one lipopeptide, wherein the polyene fungicide is natamycin and the at least one lipopeptide comprises one or more fengycin-type compounds and one or more iturin-type compounds and wherein the weight to weight ratio of the polyene fungicide and the at least one lipopeptide is about 1:1.
8. The method of claim 7 wherein the at least one lipopeptide further comprises one or more surfactin-type compounds.