IP Library › Granted Patent US 9,034,862
Granted Patent B2
US 9,034,862 · App. 13/529,965 · Granted May 19, 2015

Compositions and methods for the treatment of cancer

Inventors: Stephen J. Lippard (Cambridge, MA); Ga Young Park (Cambridge, MA)
Assignee: Massachusetts Institute of Technology
C07F15/0093
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Quick Facts
Patent No.
US 9,034,862
App. No.
13/529,965
Granted
May 19, 2015
Kind
B2
Abstract

The present invention relates to compositions, kits, and methods for treatment of cancers. In some cases, the composition comprises a platinum compound comprising a phenanthridine ligand.

Claims (19)

1. A composition comprising a compound having the structure:

wherein

X − is a counterion.

2. A pharmaceutical composition, comprising:

a composition of claim 1 ; and

one or more pharmaceutically acceptable carriers, additives and/or diluents.

3. A kit for the treatment of cancer, comprising:

a composition of claim 1 ; and

instructions for use of the composition for treatment of cancer.

4. A method of treating cancer in a patient in need of treatment for cancer, comprising:

administering a composition of claim 1 to the patient.

5. The composition of claim 1 , wherein the compound has the structure:

6. A pharmaceutical composition, comprising:

a composition of claim 5 ; and

one or more pharmaceutically acceptable carriers, additives and/or diluents.

7. A kit for the treatment of cancer, comprising:

a composition of claim 5 ; and

instructions for use of the composition for treatment of cancer.

8. A method of treating cancer in a patient in need of treatment for cancer, comprising: administering a composition of claim 5 to the patient.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 18, 2012
From: LIPPARD, STEPHEN J.; PARK, GA YOUNG
To: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Reel/Frame 029148/0549 →
CONFIRMATORY LICENSE Recorded Aug 14, 2012
From: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 028785/0923 →
Continuity (3)
Provisional Application 61499439 · Jun 21, 2011
Provisional Application 61506808 · Jul 12, 2011
Related Publication 20130029959A1 · Jan 31, 2013