Neutron Source for Neutron Capture Therapy
A therapy apparatus for producing thermal neutrons at a tumor site in a patient has a plurality of fast neutron sources surrounding a moderator, a fast neutron reflecting media around the fast neutron sources, a gamma-ray and neutron shielding media surrounding the fast neutron reflecting media, and a patient chamber positioned inside the moderator. The fast neutron sources are positioned around the moderator to maximize and direct the neutron flux to said tumor site.
1 . A therapy apparatus for producing thermal neutrons at a tumor site in a patient comprising:
a plurality of fast neutron sources surrounding a moderator;
a fast neutron reflecting media around the fast neutron sources;
a gamma-ray and neutron shielding media surrounding the fast neutron reflecting media; and
a patient chamber positioned inside the moderator;
wherein the fast neutron sources are positioned around the moderator to maximize and direct the neutron flux to said tumor site.
2 . The therapy apparatus according to claim 1 wherein the moderator maximizes the neutron flux, delivers a uniform dose and a high and uniform therapeutic ratio across the cancer site.
3 . The therapy apparatus according to claim 1 wherein the patient chamber's position and material of the moderator are selected to produce the maximum, uniform thermal neutron flux and uniform therapeutic ratio at the said tumor sites.
4 . The therapy apparatus according to claim 1 wherein the fast neutron sources are positioned at a fixed radius and equally spaced in a circle around the moderator.
5 . The therapy apparatus according to claim 1 wherein the fast neutron sources are moveable and positioned to maximize the neutron flux at the cancer site.
6 . The therapy apparatus according to claim 1 wherein said fast neutron sources are moveable and are positioned to maximize the neutron flux at the cancer site, to deliver a uniform dose across the cancer site greater than 1 Gy per session with a 10% or less variation, and to deliver a therapeutic ratio at the cancer site greater than 2, and with a uniformity across the cancer site of 10% or less variation.
7 . A therapy apparatus according to claim 1 wherein said moderator is cylindrical in shape.
8 . A therapy apparatus according to claim 1 wherein the moderator is hemispherical in shape.
9 . The therapy apparatus according to claim 1 wherein the moderator is ellipsoidal in shape.
10 . A therapy apparatus for producing thermal neutrons at tumor sites in a patient comprising:
a plurality of fast neutron sources;
a moderator disposed inside the fast neutron sources;
a patient chamber disposed inside and center of the moderator; and,
a neutron reflector and shielding apparatus disposed around the fast neutron generating target.
11 . A therapy apparatus for producing thermal neutrons at a tumor site in a patient comprising:
a plurality of ion sources;
a cylindrical electron shield disposed coaxially inside the said ion sources;
a cylindrical fast-neutron generating target disposed coaxially inside said electron shield that includes an ion entrance aperture disposed to have ions emitted from the ion source impact a fast-neutron-generating target;
a cylindrical moderator disposed coaxially inside the said cylindrical fast-neutron-generating target;
a patient chamber disposed coaxially inside said cylindrical moderator; and
a neutron reflection and shielding means disposed coaxially around said ion beam sources.