IP Library Granted Patent US 8,968,801
Granted Patent B1
US 8,968,801 · App. 13/573,385 · Granted Mar 3, 2015

Supplement composition for supporting DNA repair and method of use

Inventor: Vincent C. Giampapa (Montclair, NJ)
Assignee: Cellhealth Technologies Ltd.
A61K36/74A61K31/05A61K31/465A61K31/6615A61K36/282A61K36/31
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,968,801
App. No.
13/573,385
Granted
Mar 3, 2015
Kind
B1
Abstract

Disclosed is a supplement composition for enhancing DNA repair process, comprising effective amounts of a carotenoid compound; a nicotinamide compound; a zinc compound; inositol hexaphosphate; water extract of uncaria tomentosa ; trans-resveratrol; extract of arabidosis thaliana ; extract of cauliflower; and extract of artemisia plants.

Claims (20)

1. A method for enhancing DNA repair processes in a person in need thereof comprising orally administering a supplement composition to the person daily, said composition comprising in one dosage: from about 2,500 IU to about 10,000 IU of beta-carotene, from about 75 mg to about 500 mg of niacinamide, from about 5 mg to about 20 mg of zinc citrate, from about 250 mg to about 400 mg of inositol hexaphosphate, from about 100 mg to about 175 mg of a water extract of Uncaria tomentosa ; from about 175 mg to about 200 mg of trans-resveratrol, from about 5 mg to about 8 mg of an extract of Arabidopsis thaliana ; from about 25 mg to about 35 mg of an extract of cauliflower; and from about 20 mg to about 30 mg of an extract of Artemisia asiatica.

2. The method of claim 1 wherein the DNA repair process corrects DNA damage selected from the group consisting of single stranded DNA breaks, double stranded DNA breaks, cross-link damage, and base excision repair.

3. The method of claim 1 wherein the beta carotene is present in an amount of 5000 IU.

4. The method of claim 1 wherein the supplement composition is in the form of a tablet, a capsule, or a liquid.

5. The method of claim 1 wherein the extract of Uncaria tormentosa contains 4% to 15% carboxy alkyl esters.

6. The method of claim 1 wherein the supplement composition further comprises 8-oxoguanine glucosylase.

7. The method of claim 1 wherein the supplement composition further comprises a pharmaceutically acceptable medium.

8. The method of claim 7 wherein the pharmaceutically acceptable medium is selected from the group consisting of coloring, flavoring, diluting agents, emulsifying agents, suspending agents, ointment bases, pharmaceutical solvents, antioxidants and preservatives.

9. The method of claim 1 further comprising administering the supplement composition in conjunction with a dietary supplement.

10. The method of claim 1 wherein the supplement further comprises a diluting agent.

11. The method of claim 10 further comprising administering the supplement composition in conjunction with a dietary supplement.

12. The method of claim 10 wherein the diluting agent comprises calcium phosphate, calcium sulfate, lactose, kaolin, mannitol, sodium chloride, dry starch, powdered sugar, silica, or combinations thereof.

13. The method of claim 1 wherein the supplement composition further comprises a binder.

14. The method of claim 13 wherein the binder further comprises starch; gelatin; sugars, such as sucrose, glucose, dextrose, molasses, and lactose; natural and synthetic gums, such as acacia, sodium alginate, extract of Irish moss, panwar gum, ghatti gum, mucilage of isapol husks, carboxymethylcellulose, methylcellulose, polyvinylpyrrolidone, Veegum, microcrystalline cellulose, microcrystalline dextrose, amylose, and larch arabogalactan.

15. The method of claim 14 further comprising administering the supplement composition in conjunction with a dietary supplement.

16. The method of claim 7 wherein the pharmaceutically acceptable medium comprises dicalcium phosphate, microcrystalline cellulose, croscarmellose sodium, stearic acid, magnesium stearate, silica, and pharmaceutical glaze.

17. The method of claim 1 wherein administration of the supplement composition occurs twice daily.

18. The method of claim 17 further comprising administering the supplement composition in conjunction with a dietary supplement.

19. The method of claim 1 wherein the administration of the supplement composition is to a person having early indication of disorders related to DNA damages.

20. The method of claim 19 further comprising administering the supplement composition in conjunction with a dietary supplement.

Assignments (4)
SECURITY INTEREST Recorded Jan 8, 2026
From: LIFE SCIENCE INSTITUTE, LLC
To: TRAILBLAZE HOLDINGS LLC
Reel/Frame 073412/0468 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 24, 2018
From: CELLHEALTH TECHNOLOGIES, LLC
To: LIFE SCIENCE INSTITUTE, LLC
Reel/Frame 047291/0692 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 3, 2014
From: GIAMPAPA, VINCENT, M.D.
To: LIFE SCIENCE INSTITUTE, LLC.
Reel/Frame 032337/0291 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 3, 2014
From: LIFE SCIENCE INSTITUTE, LLC.
To: CELLHEALTH TECHNOLOGIES LTD.
Reel/Frame 032337/0806 →
Continuity (1)
Provisional Application 61534637 · Sep 14, 2011