NEO-TRYPTOPHAN
Methods of inducing antinociception in a human are described. The method includes the step of administering an effective dose of a polypeptide comprising L-neo-tryptophan to the human extracranially. The polypeptide containing L-neo-tryptophan could be, but is not limited to, NT64L, NT65L, NT66L, NT67L, NT69L, NT69L′, NT71, NT72, NT73, NT74, NT75, NT76, or NT77.
1 . A method of inducing antinociception in a human, said method comprising administering an effective dose of a polypeptide comprising L-neo-tryptophan to the human extracranially.
2 . The method of claim 1 , wherein the polypeptide is selected from the group consisting of NT64L, NT65L, NT66L, NT67L, NT69L, NT69L, NT71, NT72, NT73, NT74, NT75, NT76, and NT77.
3 . A method of inducing antinociception in a human, said method comprising administering an effective dose of one or more of NT64L, NT65L, NT66L, NT67L, NT69L, NT69L′, NT71, NT72, NT73, NT74, NT75, NT76, and NT77.