Integrated particle trap for capillary plot columns
A porous layer open tubular (PLOT) column includes capillary tubing; one or two particle traps disposed inside one or two end sections of the capillary tubing; and a stationary phase comprising a porous or non-porous material coated inside a main section of the capillary tubing. A method for preparing a porous layer open tubular (PLOT) column includes preparing one or two particle traps inside one or two end sections of a capillary tubing; and preparing a stationary phase comprising a layer of a porous material coated inside a main section of the capillary.
1. A porous layer open tubular (PLOT) column, comprising:
a capillary tubing;
two integrated particle traps disposed inside two end sections of the capillary tubing; and
a stationary phase comprising a porous layer coated inside a main section of the capillary tubing,
wherein there is no connector between the capillary tubing and either of the two integrated particle traps.
2. The PLOT column of claim 1 , wherein the capillary tubing comprises a glass or metal capillary.
3. The PLOT column of claim 1 , wherein each of the integrated particle traps comprises a product of a silicon compound, polysiloxane or wax.
4. The PLOT column of claim 3 , wherein each of the integrated particle traps comprises a product of a polysiloxane.
5. The PLOT column of claim 1 , wherein the porous layer in the stationary phase comprises a polymer.
6. The PLOT column of claim 5 , wherein the polymer is a divinylbenzene polymer or a styrene-divinylbenzene copolymer.
7. A method for preparing a porous layer open tubular (PLOT) column, comprising:
preparing two integrated particle traps inside two end sections of a capillary tubing; and
preparing a stationary phase comprising a porous layer coated inside a main section of the capillary,
wherein there is no connector between the capillary tubing and either of the two integrated particle traps.
8. The method of claim 7 , wherein the capillary tubing is a glass or metal capillary.
9. The method of claim 8 , further comprising deactivating the glass or metal capillary.
10. The method of claim 9 , wherein deactivating the glass or metal capillary is performed prior to preparing two integrated particle traps.
11. The method of claim 7 , wherein preparing two integrated particle traps is performed prior to preparing the stationary phase.
12. The method of claim 7 , wherein preparing two integrated particle traps is performed after preparing the stationary phase.
13. The method of claim 7 , wherein preparing two integrated particle traps and preparing the stationary phase are performed in one step.
14. The method of claim 7 , wherein preparing two integrated particle traps is performed by placing the particle traps directly over the stationary phase.
15. The method of claim 7 , wherein preparing the stationary phase involves in-situ polymerization.
16. The method of claim 7 comprising all treatments in one step.
17. The method of claim 7 , wherein the two integrated particle traps each comprise a product of a polysiloxane.
18. A method for preparing a porous layer open tubular (PLOT) column having two integrated particle traps disposed at the two end sections, comprising:
stripping a first section of a stationary phase coating from a first end of a PLOT column;
preparing a first particle trap in the stripped first section;
stripping a second section of a stationary phase coating from a second end of a PLOT column; and
preparing a second particle trap in the stripped second section,
wherein there is no connector between the capillary tubing and either of the two integrated particle traps.