IP Library Granted Patent US 8,551,568
Granted Patent B2
US 8,551,568 · App. 13/622,136 · Granted Oct 8, 2013

Substrate-independent layer-by-layer assembly using catechol-functionalized polymers

Inventors: Phillip B. Messersmith (Clarendon Hills, IL); Haeshin Lee (Chicago, IL); Yuhan Lee (Daejeon, KR); Zhongqiang Liu (Evanston, IL); Lesley Hamming (Durham, NC)
Assignee: Northwestern University
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Quick Facts
Patent No.
US 8,551,568
App. No.
13/622,136
Granted
Oct 8, 2013
Kind
B2
Abstract

The present invention provides a simple, non-destructive and versatile method that enables layer-by-layer (LbL) assembly to be performed on virtually any substrate. A novel catechol-functionalized polymer which adsorbs to virtually all surfaces and can serve as a platform for LbL assembly in a surface-independent fashion is also provided.

Claims (11)

1. A substrate independent method for the layer-by-layer assembly of a multifunctional film comprising the steps of: (a) contacting a substrate with a first catechol-functionalized poly(ethyleneimine) polymer to form a first layer; (b) rinsing the substrate with neat solvent; (c) contacting the substrate with a second catechol-functionalized polymer to form a second layer; (d) rinsing the substrate with neat solvent, wherein steps (a) through (d) are repeated until a multifunctional multilayer film is formed.

2. The method of claim 1 wherein the first catechol-functionalized poly(ethyleneimine) polymer comprises the structure:

wherein “n” has a value in the range from 10 to 10,000;

wherein each “m” has a value in the range of from 1 to 5,000;

wherein the second catechol-functionalized polymer comprises the structure:

wherein “x” has a value in the range from 10 to 10,000; and

wherein “y” has a value in the range from 1 to 5,000.

3. A substrate independent method for the layer-by-layer assembly of a multifunctional film comprising the steps of: (a) contacting a substrate with a first catechol-functionalized poly(ethyleneimine) polymer to form a first layer; (b) rinsing the substrate with neat solvent; (c) contacting the substrate with a second substance having an affinity for the first layer to form a second layer; (d) rinsing the substrate with neat solvent, wherein steps (a) through (d) are repeated until a multifunctional multilayer film is formed.

4. The method of claim 3 wherein the first catechol-functionalized poly(ethyleneimine) polymer comprises the structure:

wherein “n” has a value in the range from 10 to 10,000 and

wherein each “m” has a value in the range of from 1 to 5,000.

Assignments (2)
CONFIRMATORY LICENSE Recorded Apr 10, 2014
From: NORTHWESTERN UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 032653/0008 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 19, 2012
From: MESSERSMITH, PHILLIP B.; HAMMING, LESLEY; LEE, HAESHIN; LEE, YUHAN; LIU, ZHONGQIANG
To: NORTHWESTERN UNIVERSITY
Reel/Frame 029319/0082 →
Continuity (3)
Continuation 12267822 · Nov 10, 2008
Provisional Application 60986847 · Nov 9, 2007
Related Publication 20130017332A1 · Jan 17, 2013