METHODS FOR IMPROVING LINEAR GROWTH RESPONSE IN CHILDREN
Embodiments of the invention generally relate to methods and supplements for increasing linear growth in borderline GH deficient and non-GH deficient children.
1 . A method of increase linear growth in borderline GH deficient and non-GH deficient children, comprising:
providing an oral nutritional supplement, comprising:
L-arginine;
Oxo-proline; and
L-lysine; and
orally administering the nutritional supplement to a borderline GH deficient or non-GH deficient child.
2 . The method of claim 1 , wherein the L-arginine hydrochloride is present in an amount from 0.1 to 6 moles, and the oxo-proline is present in an amount from 0.1 to 8 moles.
3 . The method of claim 1 , wherein the L-lysine is present in an amount from 0.1 to 12 moles.
4 . The method of claim 1 , wherein the L-arginine is present in an amount from 2.5 to 4.5 moles, and the oxo-proline is present in an amount from 4 to 6 moles.
5 . (canceled)
6 . The method of claim 1 , wherein the nutritional supplement is present in an amount of 2.9 grams.
5 . (canceled)
7 . The method of claim 1 , wherein the nutritional supplement is administered from one to three times daily.
8 . The method of claim 1 , wherein the nutritional supplement is administered once a week.
9 . The method of claim 1 , wherein the nutritional supplement is administered on an empty stomach.
10 . A method of increase linear growth in borderline GH deficient and non-GH deficient children, comprising:
providing an oral nutritional supplement, comprising:
L-arginine hydrochloride;
oxo-proline;
L-lysine hydrochloride; and
N-acetyl-L-cysteine, L-glutamine, or both;
wherein the L-arginine hydrochloride and the oxo-proline are present in a 1:1 weight ratio; and
orally administering the nutritional supplement to a borderline GH deficient and non-GH deficient child.
11 . The method of claim 10 , wherein the nutritional supplement is present in an amount of 2.9 grams.
12 . The method of claim 10 , wherein the nutritional supplement is in powder, tablet, capsule, liquid, or wafer form.
13 . The method of claim 10 , wherein the nutritional supplement is administered from one to three times daily.
14 . The method of claim 10 , wherein the nutritional supplement is administered once a week.
15 . The method of claim 10 , wherein the nutritional supplement is administered on an empty stomach.
16 . The method of claim 10 , further comprising L-glutamine.
17 . The method of claim 10 , further comprising schizonepeta powder.
18 . A method of increase linear growth in borderline GH deficient and non-GH deficient children, comprising:
providing an oral nutritional supplement comprising an amino acid mixture, wherein the amino acid mixture consists essentially of:
L-arginine hydrochloride,
oxo-proline,
L-lysine hydrochloride, and
N-acetyl-L-cysteine, L-glutamine, or both; and
orally administering the nutritional supplement to a borderline GH deficient and non-GH deficient child.
19 . The method of claim 1 , wherein the L-lysine is present in an amount from 7 to 9 moles.
20 . The method of claim 1 , wherein the nutritional supplement is in powder, tablet, capsule, liquid, or wafer form.