IP Library Granted Patent US 9,198,889
Granted Patent B2
US 9,198,889 · App. 13/623,101 · Granted Dec 1, 2015

Methods for treating post-traumatic stress disorder

Inventors: Amy L. Heaton (Salt Lake City, UT); Mitchell K. Friedlander (Salt Lake City, UT); Dennis Gay (Salt Lake City, UT)
Assignee: QUALITY IP HOLDINGS, LLC
A61K31/198A23L1/00A61K31/4015A61K36/538
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Quick Facts
Patent No.
US 9,198,889
App. No.
13/623,101
Granted
Dec 1, 2015
Kind
B2
Abstract

Embodiments herein relate to nutritional supplements for treating post-traumatic stress disorder in human beings, and to methods of using the same. In particular examples, the nutritional supplement comprises an amino acid secretagogue composition.

Claims (29)

1. A method of improving sleep and enhancing memory in a subject in need thereof, the method comprising:

orally administering a nutritional supplement composition in unit dosage form to the subject, wherein the unit dosage consists of:

0.1 to 6 mmol L-arginine;

0.1 to 8 mmol Oxo-proline;

0.1 to 12 mmol L-lysine;

0.001 to 6 mmol N-acetyl L-cysteine; and

0.001 to 6 mmol L-glutamine.

2. The method of claim 1 , wherein the L-arginine is L-arginine HCl salt, or L-lysine is L-lysine HCl salt, or both.

3. The method of claim 1 , wherein the unit dosage form has a mass of 2.9 grams.

4. The method of claim 1 , wherein the unit dosage form is a powder, tablet, capsule, liquid, or wafer.

5. The method of claim 1 , wherein the unit dosage form is administered to the subject from one to three times daily.

6. The method of claim 1 , wherein the unit dosage form is administered to the subject once a week.

7. The method of claim 1 , wherein the unit dosage form is administered to the subject on an empty stomach.

8. The method of claim 1 , wherein the subject is a female.

9. The method of claim 1 , wherein the subject exhibits one or more of: re-experiencing an original trauma through flashbacks or nightmares, avoidance of stimuli associated with an original trauma, increased arousal, difficulty falling or staying asleep, anger, and hypervigilance.

10. A method for improving sleep in a human subject in need thereof, the method comprising:

orally administering a nutritional supplement composition in unit dosage form to the human subject, wherein the unit dosage consists of:

0.1 to 6 mmol L-arginine;

0.1 to 8 mmol Oxo-proline;

0.1 to 12 mmol L-lysine;

0.001 to 6 N-acetyl L-cysteine;

0.001 to 6 L-glutamine; and

about 125 μg Schizonepeta aerial parts powder.

11. The method of claim 10 , wherein the nutritional supplement is provided in an amount of 2.9 grams.

12. The method of claim 10 , wherein the nutritional supplement is provided in powder, tablet, capsule, liquid, or wafer form.

13. The method of claim 10 , wherein the nutritional supplement is administered from one to three times daily.

14. The method of claim 10 , wherein the nutritional supplement is administered once a week.

15. The method of claim 10 , wherein the nutritional supplement is administered on an empty stomach.

16. The method of claim 10 , wherein the subject is female.

Assignments (6)
RELEASE OF SECURITY INTEREST Recorded Jan 5, 2023
From: CASPAR CAPITAL LP
To: QUALITY IP HOLDINGS LLC
Reel/Frame 062283/0073 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 2, 2022
From: CERBERUS BUSINESS FINANCE, LLC
To: CASPAR CAPITAL LP
Reel/Frame 061636/0625 →
ASSIGNMENT OF SECURITY INTEREST Recorded Dec 30, 2019
From: LS2, LLC
To: CERBERUS BUSINESS FINANCE, LLC
Reel/Frame 051447/0114 →
SECURITY INTEREST Recorded Aug 21, 2015
From: QUALITY IP HOLDINGS, LLC
To: LS2, LLC
Reel/Frame 036392/0053 →
ASSIGNMENT FOR SECURITY - PATENTS Recorded Dec 4, 2014
From: QUALITY IP HOLDINGS, LLC
To: CERBERUS BUSINESS FINANCE, LLC, AS COLLATERAL AGENT
Reel/Frame 034535/0294 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 4, 2013
From: HEATON, AMY L; FRIEDLANDER, MITCHELL K; GAY, DENNIS
To: QUALITY IP HOLDINGS, LLC
Reel/Frame 031717/0462 →
Continuity (1)
Related Publication 20140079823A1 · Mar 20, 2014