Standardized measurement of physiological pressures using an air-charged catheter apparatus
Systems and methods are provided for providing a standardized pressure value representing a transient pressure event within a region of interest within a living body. An air-charged catheter is configured to record pressure data representing the region of interest. A measurement assembly includes a parameter calculation component configured to calculate at least a peak pressure representing the transient pressure event and a time to peak pressure, representing the time necessary to reach the peak pressure, from the recorded pressure data. A standardization component is configured to calculate the standardized pressure value as a function of the peak pressure and the time to peak pressure. A user interface is configured to display at least the standardized pressure value at an associated display.
1. A system for providing a standardized pressure value representing a transient pressure event within a region of interest within a living body comprising:
an air-charged catheter that records pressure data representing the region of interest; and
a measurement assembly, comprising a processor and at least one non-transitory computer readable medium storing executable instructions executable by the processor, the measurement assembly calculates at least a peak pressure representing the transient pressure event and a time to peak pressure, representing the time necessary to reach the peak pressure, from the recorded pressure data and
calculates the standardized pressure value, representing a peak pressure that would be expected for a water-filled catheter given the determined peak pressure, as a function of the peak pressure and the time to peak pressure; and
a user interface that displays at least the standardized pressure value.
2. The system of claim 1 , wherein the measurement assembly calculates the standardized pressure value as a product of the calculated peak pressure and a function of the time to peak pressure.
3. The system of claim 2 , wherein measurement assembly calculates the standardized pressure value as the product of the calculated peak pressure and the ratio of an exponential function of the time to peak pressure to the difference between the exponential function of the time to peak pressure and a predetermined constant.
4. A system for providing a standardized pressure value representing a transient pressure event within a region of interest within a living body comprising:
an air-charged catheter that records pressure data representing the region of interest; and
a measurement assembly that calculates at least a peak pressure representing the transient pressure event and a time to peak pressure, representing the time necessary to reach the peak pressure, from the recorded pressure data, calculates a peak pressure that would be expected for a water-filled catheter given the determined peak pressure at the air-charged catheter, as a function of the peak pressure at the air-charged catheter and the time to peak pressure at the air-charged catheter; and
a user interface that displays at least the peak pressure that would be expected for a water-filled catheter given the determined peak pressure at the air-charged catheter.
5. The system of claim 4 , wherein the measurement assembly calculates the peak pressure that would be expected for a water-filled catheter given the determined peak pressure at the air-charged catheter as a product of the calculated peak pressure at the air-charged catheter and a function of the time to peak pressure at the air-charged catheter.
6. The system of claim 5 , wherein the measurement assembly calculates the peak pressure that would be expected for a water-filled catheter given the determined peak pressure at the air-charged catheter as the product of the calculated peak pressure at the air-charged catheter and the ratio of an exponential function of the time to peak pressure at the air-charged catheter to the difference between the exponential function of the time to peak pressure at the air-charged catheter and a predetermined constant.
7. The system of claim 6 , wherein the predetermined constant is three-hundredths of a second.
8. The system of claim 7 , wherein the peak pressure at the air-charged catheter, P peak , is measured in centimeters of water and the exponential function of the time to peak pressure at the air-charged catheter T pp , is equal to the time to peak pressure, at the air-charged catheter taken to a power of 1.184, such that:
P
Std
=
P
peak
*
T
PP
1.184
T
PP
1.184
-
0.03
where P std is the peak pressure that would be expected for a water-filled catheter given the determined peak pressure at the air-charged catheter.
9. The system of claim 4 , wherein the measurement assembly determines the peak pressure at the air-charged catheter as a difference between a baseline pressure and a maximum recorded pressure at the air-charged catheter.
10. The system of claim 9 , wherein the measurement assembly determines the time to peak pressure at the air-charged catheter as the length of time necessary for the pressure to increase from five percent of the maximum recorded pressure to the maximum recorded pressure.
11. The system of claim 4 , the measurement assembly further comprising a data conditioning element that receives recorded pressure data from the air-charged catheter and places it in an appropriate form for analysis at the parameter calculation component.
12. The system of claim 11 , the data conditioning element comprising a filter to process the recorded pressure data to remove noise and artifact.