Granted Patent
B2
US 9,034,857 · App. 13/636,785 · Granted May 19, 2015
Methods for reducing superoxide anions in eukaryotic organisms
Inventors:
William C. Burhans (Buffalo, NY); Catherine E. Prudom Gineste (Harrisonburg, VA); Christopher P. Allen (Fort Collins, CO); Oleg Ursu (Albuquerque, NM); Anna Waller (Albuquerque, NM); Larry A. Sklar (Albuquerque, NM)
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Abstract
Provided are methods and compositions for reducing superoxide anions such that a prophylactic or therapeutic effect against conditions associated with excess oxidative stress achieved. The compositions and methods provide for reducing inflammation and for enhancing lifespan of eukaryotic organisms. A screen for identifying compounds that can be used in these methods is also provided.
Claims (2)
1. A method for reducing intracellular superoxide anions in a eukaryotic organism comprising administering to the eukaryotic organism a composition comprising a compound having a structure,
wherein R 10 is H or an alkyl.
Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 11, 2013
From: BURHANS, WILLIAM C.
To: HEALTH RESEARCH, INC.
Reel/Frame 029787/0955 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jan 29, 2013
From: ALLEN, CHRISTOPHER P.; PRUDOM, CATHERINE E.; SKLAR, LARRY A.; WALLER, ANNA; URSU, OLEG
To: THE REGENTS OF THE UNIVERSITY OF NEW MEXICO
Reel/Frame 029716/0441 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jan 29, 2013
From: THE REGENTS OF THE UNIVERSITY OF NEW MEXICO
To: STC.UNM
Reel/Frame 029716/0469 →
CONFIRMATORY LICENSE
Recorded Dec 18, 2012
From: ROSWELL PARK CANCER INSTITUTE
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 029490/0673 →
Continuity (5)
Provisional Application
61317056
· Mar 24, 2010
Provisional Application
61346275
· May 19, 2010
Provisional Application
61347992
· May 25, 2010
Provisional Application
61361111
· Jul 2, 2010