IP Library Granted Patent US 9,700,455
Granted Patent B2
US 9,700,455 · App. 13/645,706 · Granted Jul 11, 2017

Methods and devices for prevention of hypothermia in a mammal during prolonged exposure to extreme cold

Inventors: Dennis A. Grahn (Palo Alto, CA); H. Craig Heller (Stanford, CA)
Assignee: The Board of Trustees of the Leland Stanford Junior University
A61F7/12A61F7/02A61F2007/0029A61F2007/0036A61F2007/0039A61F2007/0055A61F2007/0086A61F2007/0239
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Quick Facts
Patent No.
US 9,700,455
App. No.
13/645,706
Granted
Jul 11, 2017
Kind
B2
Abstract

Methods and devices for preventing a change in the core body temperature of a mammal under cold conditions are provided. In the subject methods, a requirement for thermal energy input in said mammal is first detected. In response to the detection of this requirement for thermal energy input, a surface of a portion of the mammal is contacted with a warm temperature medium under negative pressure conditions for a period of time sufficient to introduce thermal energy into the core body of the mammal. The subject devices include at least a means for detecting a requirement for thermal energy input and a means for contacting a surface of the mammal with a warm temperature medium under negative pressure conditions. The subject methods and devices find use in a variety of applications, and are particularly suited for use in maintaining the core body temperature of a mammal substantially constant under cold conditions for an extended period of time.

Claims (15)

1. A method for preventing a change in a human's core body temperature under cold conditions, said method comprising:

(a) detecting a requirement for thermal energy input in said human; and

(b) contacting a surface or a portion of a surface of either an arm or a leg of said human in response to detecting said requirement with a warm temperature medium under negative pressure conditions for a period of time sufficient to introduce thermal energy into the core body of said human;

whereby the core body temperature of said human is prevented from changing under said cold conditions.

2. The method according to claim 1 , wherein said requirement is detected by detecting the presence of a thermoregulatory error in said human.

3. The method according to claim 2 , wherein said thermoregulatory error is detected by detecting the presence of vasoconstriction in said human.

4. The method according to claim 1 , wherein said method further comprises enclosing said portion of said human in a sealed enclosure to produce an enclosed portion of said human.

5. The method according to claim 1 , wherein said method is a method of maintaining said core body temperature of said human substantially constant for a temporal duration of at least about 60 min and said method comprises performing steps (a) and (b) at least twice during said temporal duration.

6. The method according to claim 4 , wherein said sealed enclosure has a pressure ranging from about −20 to −80 mm Hg.

7. The method according to claim 1 , wherein said warm temperature medium has a temperature ranging from about 44 to 48° C.

8. The method according to claim 1 , wherein said period of time ranges from about 1 to 600 min.

9. A method for maintaining the core body temperature of a human substantially constant for a temporal duration of at least about 60 min under cold conditions, said method comprising:

(a) monitoring said human during said temporal duration for the presence of a thermoregulatory error; and

(b) contacting a surface of an enclosed portion of an arm or a leg of said human in response to the presence of said thermoregulatory error with a warm temperature medium under negative pressure conditions for a period of time sufficient to introduce thermal energy into the core body of said human;

whereby the core body temperature of said human is maintained substantially constant during said temporal duration.

Assignments (2)
CONFIRMATORY LICENSE Recorded Oct 14, 2015
From: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
To: US ARMY, SECRETARY OF THE ARMY
Reel/Frame 036861/0844 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 15, 2013
From: GRAHN, DENNIS A.; HELLER, H. CRAIG
To: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Reel/Frame 029633/0789 →
Continuity (6)
Continuation 12955769 · Nov 29, 2010
Continuation 11213323 · Aug 26, 2005
Continuation 10655557 · Sep 3, 2003
Continuation 09877407 · Jun 7, 2001
Provisional Application 60210664 · Jun 9, 2000
Related Publication 20130103128A1 · Apr 25, 2013