METHOD OF TREATING PANCREATIC CANCER
A therapeutic method for treating pancreatic cancer is disclosed comprising administering to a patient in need of treatment a gallium complex according to Formula (I) provided herein.
1 . A method of treating pancreatic cancer, comprising:
identifying a patient having pancreatic cancer; and
treating the patient with a therapeutically effective amount of an effective amount of a gallium complex of Formula (I)
wherein R 1 represents hydrogen, a halogen or a sulfono group SO 3 M, in which M is a metal ion, and R 2 represents hydrogen, or R 1 is C 1 and R 2 is I, or a pharmaceutically acceptable salt thereof.
2 . A method of treating, or delaying the onset of, a refractory pancreatic cancer, comprising administering to a patient in need thereof a prophylactically effective amount of an effective amount of a gallium complex of Formula (I)
wherein R 1 represents hydrogen, a halogen or a sulfono group SO 3 M, in which M is a metal ion, and R 2 represents hydrogen, or R 1 is C 1 and R 2 is I, or a pharmaceutically acceptable salt thereof.
3 . The method of claim 2 , wherein said patient has previously been treated with a regimen comprising gemcitabine.
4 . The method of claim 2 , wherein said patient has previously been treated with a regimen comprising erlotinib.
5 . The method according to claim 3 , wherein said compound is tris(8-quinolinolato)gallium(III).
6 . The method according to claim 4 , wherein said compound is tris(8-quinolinolato)gallium(III).