IP Library Granted Patent US 9,121,841
Granted Patent B2
US 9,121,841 · App. 13/697,916 · Granted Sep 1, 2015

Pipetting arrangement and method of controlling a pipetting arrangement or of producing liquid product doses

Inventor: Pius Fink (Hombrechtikon, CH)
Assignee: Sias AG
G01N35/1072B01L3/021B01L2300/0861B01L2400/0487Y10T137/0318
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Quick Facts
Patent No.
US 9,121,841
App. No.
13/697,916
Granted
Sep 1, 2015
Kind
B2
Abstract

The invention relates to a pipetting arrangement comprising at least two sets of pipettes ( 9 a; 9 b; 9 c; 9 d ). Each set of pipettes ( 9 a; 9 b; 9 c; 9 d ) is operationally connected, via a controllable ON/OFF valve ( 11 a; 11 b; 11 e; 11 d ) to a common aspiration port ( 7 ). Latter is connectable to a pumping arrangement ( 3 ). The valves ( 11 a; 11 b; 11 e; 11 d ) are controlled by a timing-control unit ( 15 ) conceived to establish, by control of the valves ( 11 a; 11 b; 11 e; 11 d ), the operational connections of the at least two sets of pipettes ( 9 a; 9 b; 9 c; 9 d ) to the aspiration port ( 7 ) in a time-multiplexed manner.

Claims (33)

1. A method of controlling a pipetting arrangement or of producing at least two liquid doses of predetermined volumes, comprising:

dipping a first of at least two sets of pipettes into a first reservoir containing a first liquid, operationally connecting, via a gaseous transmitter medium, said first set of pipettes to an aspiration port operationally connected to a pumping arrangement and establishing an aspirating effect at said aspiration port;

opening a first ON/OFF valve in said gaseous transmitter medium, and interconnected between said first set of pipettes and said aspiration port, thereby aspirating first liquid into said first set of pipettes;

closing said first ON/OFF valve in said gaseous transmitter medium and interconnected between said first set of pipettes and said aspiration port;

dipping a second set of said at least two sets of pipettes into a second reservoir containing a second liquid, operationally connecting via said gaseous transmitter medium, said second set of pipettes to said aspiration port operationally connected to said pumping arrangement and establishing an aspirating effect at said aspiration port;

opening a second ON/OFF valve in said gaseous transmitter medium, and interconnected between said second set of pipettes and said aspiration port, thereby aspirating second liquid into said second set of pipettes;

closing said second ON/OFF valve in said gaseous transmitter medium and interconnected between said second set of pipettes and said aspiration port;

thereby time-multiplexing said operational connections from said first set of pipettes and from said second set of pipettes to said aspiration port by respectively time-controlled opening of said first and second ON/OFF valves;

said pumping arrangement being controlled to be ongoingly operative during said multiplexing, and

establishing the volumes of said aspirated doses merely by selecting the time spans during which said valves are respectively open.

2. The method of claim 1 , comprising selecting at least one of said at least two sets of pipettes to comprise one single pipette.

3. The method of claim 1 , comprising at least one of:

said first and second liquids being different,

said first and second receptacles being two distinct receptacles,

said dippings being performed simultaneously.

4. The method of claim 1 , further comprising an additional, selectable mode of operation, wherein said operational connections of said first and second sets of pipettes to said aspiration port are simultaneously established.

5. The method of claim 1 , wherein said pumping arrangement comprises a line network and a pressurizing station in a building installation.

6. A method of controlling a pipetting arrangement or of producing at least two liquid doses of predetermined volumes, comprising:

applying a first of at least two sets of pipettes to a first reservoir for a first liquid, operationally connecting, via a gaseous transmitter medium, said first set of pipettes to a pressure port operationally connected to a pumping arrangement and establishing an ejecting effect at said pressure port;

opening a first ON/OFF valve in said gaseous transmitter medium, and interconnected between said first set of pipettes and said pressure port, thereby ejecting first liquid from said first set of pipettes;

closing said first ON/OFF valve in said gaseous transmitter medium and interconnected between said first set of pipettes and said pressure port;

applying a second set of said at least two sets of pipettes to a second reservoir for a second liquid, operationally connecting, via said gaseous transmitter medium, said second set of pipettes to said pressure port operationally connected to said pumping arrangement and establishing an ejecting effect at said pumping port;

opening a second ON/OFF valve in said gaseous transmitter medium and interconnected between said second set of pipettes and said pressure port, thereby ejecting second liquid from said second set of pipettes;

closing said second ON/OFF valve in said gaseous transmitter medium and interconnected between said second set of pipettes and said pressure port;

thereby time-multiplexing said operational connections from said first set of pipettes and from said second set of pipettes to said pressure port by respectively time-controlled opening of said first and second ON/OFF valves;

said pumping arrangement being controlled to be ongoingly operative during said multiplexing, and establishing the volumes of said ejected doses merely by selecting the time spans during which said valves are respectively open.

7. The method of claim 6 , comprising selecting at least one of said at least two sets of pipettes to comprise one single pipette.

8. The method of claim 6 , comprising at least one of:

said first and second liquids being different,

said first and second receptacles being two distinct receptacles,

said dippings being performed simultaneously.

9. the method of claim 6 , further comprising an additional, selectable mode of operation, wherein said operational connections of said first and second sets of pipettes to said aspiration port are simultaneously established.

10. The method of claim 6 , wherein said pumping arrangement comprises a line network and a pressurizing station in a building installation.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 27, 2020
From: TECAN SCHWEIZ AG
To: TECAN TRADING AG
Reel/Frame 052762/0988 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 24, 2018
From: SIAS AG
To: TECAN SCHWEIZ AG
Reel/Frame 045619/0826 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 6, 2012
From: FINK, PIUS
To: SIAS AG
Reel/Frame 029458/0077 →
Continuity (1)
Related Publication 20130056079A1 · Mar 7, 2013