Use of Tetrahydropyrimidines
A method of treatment of postoperative inflammatory stress and pain comprising administering a tetrahydropyrimidine selected from ectoine and/or hydroxyectoine to a patient in need of such treatment.
1 . A method of treatment of postoperative inflammatory stress and pain comprising administering a tetrahydropyrimidine selected from ectoine and/or hydroxyectoine to a patient in need of such treatment.
2 . The method of claim 1 , wherein the postoperative inflammatory stress and pain is pain in the abdominal and intestinal region.
3 . The method of claim 1 , wherein the postoperative inflammatory stress and pain is pain caused by transplantation in the region of the abdomen.
4 . The method of claim 1 , wherein the postoperative inflammatory stress and pain is stress and pain after endoscopic or laparoscopic interventions caused by inflammation.
5 . The method of claim 1 , wherein the tetrahydropyrimidine is hydroxyectoine.
6 . The method of claim 1 wherein the tetrahydropyrimidine is administered to a patient in an amount of 1 to 250 mg per kg of body weight and day.
7 . The method of claim 1 wherein the tetrahydropyrimidine is in the form of a solution for topical application comprising the tetrahydropyrimidine in an amount ranging between 0.1 and 25% w/w.
8 . The method of claim 6 , wherein the tetrahydropyrimidine is administered to a patient in an amount of 5 to 150 mg per kg of body weight and day.
9 . The method of claim 6 , wherein the tetrahydropyrimidine is administered to a patient in an amount of 10 to 100 mg per kg of body weight and day.
10 . The method of claim 7 , wherein the solution comprises 9.5 to 5% w/w of the tetrahydropyrimidine.