Fluorescence detection of poison oak oil
View Patent ↗The invention herein disclosed provides for compositions, methods for synthesizing said compositions, and methods for using said compositions, wherein the compositions and methods may be used to bind to and/or deactivate a poison oak oil, such as urushiol. The compositions and methods can be used to treat and/or reduce an inflammatory reaction and/or hypersensitivity to natural compounds found in poison oak, poison ivy, poison sumac, mango, lac tree, and cashew nut.
1. A kit for detecting a catechol, the kit comprising a vessel, an applicator, and a composition, the vessel shaped and adapted for confining the composition, the composition comprising a boron compound, a first nitroxide, and a second nitroxide; wherein the first nitroxide is a profluorescent nitroxide.
2. The kit of claim 1 , wherein the boron composition comprises a hydrophobic alkyl group.
3. The kit of claim 1 , wherein the applicator is a spray applicator.
4. The kit of claim 1 , wherein the catechol is urushiol.
5. The kit of claim 1 further comprising an aerosol propellant.
6. The kit of claim 1 further comprising a lamp.
7. The kit of claim 1 , further comprising a set of instructions of how to use the kit.
8. A topical composition for detecting a catechol, the topical composition comprising an effective amount of a boron compound, a nitroxide, and a suitable excipient, carrier, or combination thereof, the boron compound comprising an alkylboronic acid having the general formula R—B(OH) 2 , the boron compound in an effective amount for the detection of a catechol in poison oak oil.
9. The topical composition of claim 8 , wherein the nitroxide is a profluorescent nitroxide.
10. The topical composition of claim 8 , wherein the boron compound optionally comprises at least one B-alkyl boronic acid derivative.
11. The topical composition of claim 8 , said topical composition optionally containing xanthan gum or gellan gum.
12. The topical composition of claim 8 , wherein the effective amount of the boron compound for the detection of a catechol in poison oak oil is between about 1.005% to about 5% by weight, based on the total combined weight of the boron compound thereof, not including other excipients, carriers, or combinations thereof.
13. A topical medicament for detecting a catechol, the topical medicament comprising a boron compound, the boron compound comprising an alkylboronic acid having the general formula R—B(OH) 2 , a nitroxide, and a suitable excipient, carrier, or combination thereof, and where R is selected from the group consisting of a hydrophobic alkyl group and a hydrophilic alkyl group, the boron compound is in an effective amount for the detection of a catechol in poison oak oil.
14. The topical medicament of claim 13 , wherein the boron compound optionally comprises at least one B-alkyl boronic acid derivative.
15. The topical medicament of claim 13 , wherein the nitroxide is a profluorescent nitroxide.
16. The topical medicament of claim 13 , wherein the effective amount of the boron compound for the detection of a catechol in poison oak oil is between about 1.005% to about 5% by weight, based on the total combined weight of the boron compound thereof, not including other excipients, carriers, or combinations thereof.