Hetero-substituted acetanilide derivatives as analgesic agents
Hetero-substituted acetanilide derivatives are disclosed as analgesic agents. The compounds of the invention are useful in methods for treating a disease or condition in a mammal characterized by pain and/or fever.
1. A compound selected from the group consisting of:
5-Methyl-1H-pyrazole-3-carboxylic acid (4-hydroxy-phenyl)-amide; and
3H-Imidazole-4-carboxylic acid (4-hydroxy-phenyl)-amide;
and enantiomers, diastereomers, tautomers, or pharmaceutically acceptable salts thereof.
2. A compound of claim 1 , wherein the compound is 5-Methyl-1H-pyrazole-3-carboxylic acid (4-hydroxy-phenyl)-amide and enantiomers, diastereomers, tautomers, or pharmaceutically acceptable salts thereof.
3. A composition comprising a compound selected from the group consisting of:
5-Methyl-1H-pyrazole-3-carboxylic acid (4-hydroxy-phenyl)-amide; and
3H-Imidazole-4-carboxylic acid (4-hydroxy-phenyl)-amide;
and enantiomers, diastereomers, tautomers, or pharmaceutically acceptable salts thereof.
4. The composition of claim 3 wherein the compound is 5-Methyl-1H-pyrazole-3-carboxylic acid (4-hydroxy-phenyl)-amide and enantiomers, diastereomers, tautomers, or pharmaceutically acceptable salts thereof.