IP Library Granted Patent US 8,838,204
Granted Patent B2
US 8,838,204 · App. 13/718,141 · Granted Sep 16, 2014

System and method for phase contrast imaging with improved efficiency

Inventors: Robert R Edelman (Highland Park, IL); Christopher Glielmi (Hoboken, NJ); Ioannis Koktzoglou (Rolling Meadows, IL); Erik J Offerman (Chicago, IL)
Assignees: Siemens Medical Solutions USA, Inc.; The United States of America as represented by the National Institutes of Health (NIH); U.S. Dept of Health and Human Services (DHHS)
A61B5/0263A61B5/0044G01R33/5635A61B5/7285G01R33/5673A61B5/0402
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Quick Facts
Patent No.
US 8,838,204
App. No.
13/718,141
Granted
Sep 16, 2014
Kind
B2
Abstract

A system and method is provided for magnetic resonance angiography (MRA) that includes performing a pulse sequence using the MRI system, the pulse sequence including a phase-based flow encoding to collect a time-series of image data from the portion of the vasculature of the subject and identifying at least a portion of the time series of image data corresponding to a period of reduced flow through the portion of the vasculature. The portion of the time series of image data is subtracted from the time series of image data to create a time series of images of the portion of the vasculature having background tissue surrounding the portion of the vasculature substantially suppressed.

Claims (21)

1. A method of acquiring a magnetic resonance angiography (MRA) image of a portion of a vasculature of a subject using a magnetic resonance imaging (MRI) system, the method comprising:

performing a pulse sequence using the MRI system, the pulse sequence including a phase-based flow encoding to collect a time-series of image data from the portion of the vasculature of the subject;

monitoring, during the performing of the pulse sequence, a cardiac cycle of the subject and synchronizing the collection of the time-series of image data from the portion of the vasculature of the subject to the cardiac cycle of the subject;

identifying at least a portion of the time series of image data within the cardiac cycle and corresponding to a period of reduced flow through the portion of the vasculature; and

subtracting the portion of the time series of image data within the cardiac cycle from the time series of image data to create a time series of images of the portion of the vasculature having background tissue surrounding the portion of the vasculature substantially suppressed.

2. The method of claim 1 wherein identifying at least a portion of the time series of image data includes selecting at least one image frame to create a subtraction image.

3. The method of claim 2 wherein subtracting includes subtracting the subtraction image from each image frame reconstructed from the time series of image data.

4. The method of claim 2 wherein identifying at least a portion of the time series of image data includes selecting multiple image frames and averaging the multiple image frames to create a subtraction image.

5. The method of claim 4 wherein subtracting includes subtracting the subtraction image from each image frame reconstructed from the time series of image data.

6. The method of claim 1 wherein identifying includes selecting at least one image frame from a time series of images reconstructed from the time series of image data corresponding to reduced flow from through the portion of the vasculature.

7. The method of claim 1 wherein subtracting includes iteratively processing each image frame reconstructed from the time series of image data with respect to the identified at least a portion of the time series of image data.

8. The method of claim 1 wherein a minority of image frames is acquired using a flow-rephased gradient waveform.

9. A magnetic resonance imaging (MRI) system comprising:

a magnet system configured to generate a polarizing magnetic field about at least a portion of a subject arranged in the MRI system;

a plurality of gradient coils configured to apply a gradient field to the polarizing magnetic field;

a radio frequency (RF) system configured to apply an excitation field to the subject and acquire MR image data therefrom;

a computer system programmed to:

perform a pulse sequence using the MRI system, the pulse sequence including a phase-based flow encoding to collect a time-series of image data from the portion of the vasculature of the subject;

monitor, during the performing of the pulse sequence, a cardiac cycle of the subject and synchronize the collection of the time-series of image data from the portion of the vasculature of the subject to the cardiac cycle of the subject;

identify at least a portion of the time series of image data within the cardiac cycle and corresponding to a period of reduced flow through the portion of the vasculature; and

subtract the portion of the time series of image data within the cardiac cycle from the time series of image data to create a time series of images of the portion of the vasculature having background tissue surrounding the portion of the vasculature substantially suppressed.

Assignments (6)
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE PREVIOUSLY RECORDED AT REEL: 066088 FRAME: 0256. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jan 17, 2024
From: SIEMENS HEALTHCARE GMBH
To: SIEMENS HEALTHINEERS AG
Reel/Frame 071178/0246 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 20, 2023
From: SIEMENS HEALTHCARE GMBH
To: SIEMENS HEALTHINEERS AG
Reel/Frame 066088/0256 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 11, 2017
From: SIEMENS MEDICAL SOLUTIONS USA, INC.
To: SIEMENS HEALTHCARE GMBH
Reel/Frame 042970/0516 →
CONFIRMATORY LICENSE Recorded Jan 3, 2014
From: NORTHSHORE UNIVERSITY HEALTHSYSTEM (FORMERLY EVANSTON NORTHWESTERN HEALTHCARE)
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 031913/0980 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 3, 2013
From: GLIELMI, CHRISTOPHER
To: SIEMENS MEDICAL SOLUTIONS USA, INC.
Reel/Frame 029561/0778 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 19, 2012
From: OFFERMAN, ERIK J; KOKTZOGLOU, IONNIS, PHD; EDELMAN, ROBERT R, MD
To: NORTHSHORE UNIVERSITY HEALTHSYSTEM
Reel/Frame 029498/0549 →
Continuity (2)
Provisional Application 61586310 · Jan 13, 2012
Related Publication 20130184561A1 · Jul 18, 2013