Surface modified nanoparticles
Surface-modified nanoparticles are produced by associating ligand interactive agents with the surface of a nanoparticle. The ligand interactive agents are bound to surface modifying ligands that are tailored to impart particular solubility and/or compatibility properties. The ligand interactive agents are crosslinked via a linking/crosslinking agent, such as hexamethoxymethylmelamine or a derivative thereof. The linking/crosslinking agent may provide a binding site for binding the surface modifying ligands to the ligand interactive agents.
1. A method of functionalizing a InP/ZnS nanoparticle, comprising:
associating a ligand interactive agent consisting essentially of a C 8 -C 20 fatty acid with the nanoparticle;
crosslinking the ligand interactive agent with a linking/crosslinking agent consisting essentially of hexamethoxymethylmelamine; and
binding a surface modifying ligand to the ligand interactive agent.
2. The method of claim 1 , further comprising providing capping ligands on the nanoparticle and wherein associating a ligand interactive agent with the nanoparticle comprises intercalating the ligand interactive agent with the capping ligands.
3. The method of claim 1 , wherein the surface modifying ligand is water soluble.
4. The method of claim 1 , wherein the surface modifying ligand comprises a polyether.
5. The method of claim 1 , wherein the surface modifying ligand is a monomethoxy polyethylene glycol.
6. The method of claim 1 , wherein the surface modifying ligand comprises a silicone.
7. The method of claim 1 , wherein associating a ligand interactive agent with the nanoparticle comprises incubating the ligand interactive agent with the nanoparticle to yield a ligand interactive agent-nanoparticle association complex.
8. The method of claim 7 , wherein crosslinking the ligand interactive agent comprises contacting the ligand interactive agent-nanoparticle association complex with a solution of the hexamethoxymethylmelamine linking/crosslinking agent to effect crosslinking of the ligand interactive agent.
9. The method of claim 8 , wherein the solution of linking/crosslinking agent further comprises a catalyst.
10. The method of claim 8 , wherein the solution of linking/crosslinking agent further comprises the surface modifying ligand.
11. A functionalized nanoparticle, comprising:
a core comprising InP/ZnS;
a crosslinked ligand interactive agent consisting essentially of a C 8 -C 20 fatty acid associated with the surface of the functionalized nanoparticle; and
at least one surface modifying ligand bound to the ligand interactive agent.
12. The nanoparticle of claim 11 , wherein the ligand interactive agents are associated with the surface of the nanoparticle by intercalating with capping ligands on the nanoparticle.
13. The nanoparticle of claim 11 , wherein the ligand interactive agents are crosslinked via a linking/crosslinking agent consisting essentially of hexamethoxymethylmelamine.
14. The nanoparticle of claim 13 , wherein the surface modifying ligands are bound to the ligand interactive agent via the linking/crosslinking agent.
15. The nanoparticle of claim 11 , wherein the surface modifying ligand comprises a polyether.
16. The nanoparticle of claim 11 , wherein the surface modifying ligand comprises a silicone.
17. The nanoparticle of claim 11 , wherein the nanoparticle is water soluble.
18. The nanoparticle of claim 17 , wherein the nanoparticle has a quantum yield of greater than about 35%.
19. The nanoparticle of claim 18 , wherein the nanoparticle does not comprise cadmium.
20. A composition comprising a nanoparticle and hexamethoxymethylmelamine.
21. The composition of claim 20 , wherein the nanoparticle comprises:
a core comprising InP;
a crosslinked ligand interactive agent consisting essentially of a C 8 -C 20 fatty acid associated with the surface of the nanoparticle; and
at least one surface modifying ligand bound to the ligand interactive agent.
22. The composition of claim 21 , further comprising a polar solvent.
23. The composition of claim 22 , wherein the nanoparticle has a quantum yield of greater than about 35%.
24. The composition of claim 23 , wherein the nanoparticle does not comprise cadmium.
25. The composition of claim 24 , wherein the composition is an ink.