Composition for treating obesity and method of using the same
The present invention provides a composition for a medicinal or health effect of a treatment of liver fat and body fat, a reduction of blood pressure, an increase of the energy expenditure rate, a reduction of inflammatory C-reactive proteins and a reduction of plasma aminotransferase enzymes, comprising an effective amount of fucoxanthin alone or in combination with pomegranate seed oil, a pharmaceutically acceptable salt, a prodrug thereof, or a salt of the prodrug; and a method of using the same. The fucoxanthin may be used in pure form, or as a component of a brown marine vegetable extract.
1. A treatment method for reducing body weight reducing liver fat, reducing body fat, or reducing both liver fat and body fat, comprising the step of administering a composition to a mammal in need thereof, said composition comprising:
an extract of brown marine vegetables in an amount sufficient to provide from 10 to 25 mg/day of fucoxanthin, a pharmaceutically acceptable salt of fucoxanthin, or a mixture thereof;
pomegranate seed oil in an amount sufficient to provide from 100 to 500 mg/day of punicic acid; and
a pharmaceutically acceptable carrier,
wherein the extract of brown marine vegetables is present in an amount of from about 25 to 75 weight percent based on the total weight of the composition and the pomegranate seed oil is present in a amount of from about 25 to 75 weight percent of the composition.
2. The method of claim 1 , wherein said extract of brown marine vegetables further comprises a vegetable oil.
3. The method of claim 2 , wherein the vegetable oil comprises omega-3 fatty acids.
4. The method of claim 1 , wherein the composition is formulated in at least one dosage form.
5. The method of claim 1 , wherein the treatment method additionally reduces blood pressure, plasma aminotransferase enzymes, or C-reactive proteins; or wherein the treatment method stimulates muscle protein synthesis.
6. The method of claim 5 , wherein the treatment method additionally reduces plasma aminotransferase enzymes.
7. The method of claim 5 , wherein the treatment method additionally reduces C-reactive proteins.
8. The method of claim 5 , wherein the treatment method stimulates muscle protein synthesis.