Valve prosthesis frames
A prosthesis can include a collapsible, reexpandable frame having first, second, and third sets of struts that define first and second rows of expandable cells. In some embodiments, the struts of the first, second, and third set of struts can be tapered. In some embodiments, the frame can include an intermediate section and an inflow section that is proximal to the intermediate section. The inflow section can include a concave saddle portion that is adjacent the intermediate section, and an outwardly flared portion.
1. A prosthesis comprising:
a collapsible and re-expandable frame, the frame having an inflow edge and a longitudinal axis, the frame comprising
first, second, and third sets of struts,
wherein struts of the first set of struts are connected to adjacent struts of the first set of struts at a first plurality of nodes at the inflow edge, wherein each strut of the first set of struts comprises a first proximal segment, a first intermediate segment with a first width, and a first distal segment,
wherein the first and second sets of struts are connected at a second plurality of nodes to define a first row of expandable cells, wherein each strut of the second set of struts comprises a second proximal segment, a second intermediate segment with a second width, and a second distal segment, and wherein the second width of the second intermediate segment of each strut of the second set of struts is greater than the first width of the first intermediate segment of each strut of the first set of struts,
wherein the second and third sets of struts are connected at a third plurality of nodes to define a second row of expandable cells, the first row of expandable cells being proximal to the second row of expandable cells,
wherein each node of the second plurality of nodes has a first length,
wherein each node of the third plurality of nodes has a second length,
wherein the first length is longer than the second length, and
wherein each strut of the first set of struts comprises the first proximal segment with a fourth width, and the first distal segment with a fifth width, the fourth width being smaller than the first width of the first intermediate segment, and the first width of the first intermediate segment being smaller than the fifth width,
wherein each node of the first plurality of nodes, which together define an inflow end of the prosthesis, comprises a keyhole-shaped opening having a distal portion with a first width and a proximal portion with a second width that is greater than the first width, and wherein the distal portion of each key-hole opening opens to a corresponding expandable cell of the first row of expandable cells.
2. The prosthesis of claim 1 , wherein:
the first length ranges from about 3 mm to about 7 mm; and
the second length ranges from about 2.5 mm to about 6.5 mm.
3. The prosthesis of claim 1 , wherein a third length between centers of the first plurality of nodes and centers of the second plurality of nodes is longer than a fourth length between the centers of the second plurality of nodes and centers of the third plurality of nodes.
4. The prosthesis of claim 3 , wherein the third and fourth lengths range from about 2.5 mm to about 6.5 mm.
5. The prosthesis of claim 1 , wherein the first and second widths range from about 0.1 mm to about 1.2 mm.
6. The prosthesis of claim 1 , wherein:
the first row of expandable cells forms an outwardly flared portion at the inflow edge of the frame; and
the second row of expandable cells forms a concave saddle portion that is adjacent and distal to the outwardly flared portion.
7. The prosthesis of claim 1 , further comprising a valve body coupled to the frame.
8. The prosthesis of claim 1 , wherein the key-hole shaped openings distribute forces generated by compressing the frame away from apices of the first plurality of nodes and provide a resulting force distribution at the inflow end of the prosthesis that permits the frame to be more evenly compressed while maintaining strength thereof.
9. A prosthesis comprising:
a collapsible and re-expandable frame, the frame having an inflow edge, an outflow edge and a longitudinal axis, the frame comprising at least first, second, third and fourth sets of struts, and a plurality of coupling elements at the outflow edge of the frame,
wherein struts of the first set of struts are connected to adjacent struts of the first set of struts at a first plurality of nodes at the inflow edge,
wherein the first and second sets of struts are connected at a second plurality of nodes to define a first row of expandable cells,
wherein the second and third sets of struts are connected at a third plurality of nodes to define a second row of expandable cells, and
wherein the third and fourth sets of struts are connected at a fourth plurality of nodes to define a third row of expandable cells,
wherein in an original manufactured condition, struts axially aligned in a column with a coupling element of the plurality of coupling elements are configured to be less stiff than struts not axially aligned with the coupling element, and
wherein a width or thickness of the struts axially aligned in the column with the coupling element is smaller than a respective width or thicknesses of the struts that are not axially aligned with the coupling element.
10. The prosthesis of claim 9 , further comprising:
a valve body coupled to the frame.
11. A prosthesis comprising:
a collapsible and re-expandable frame, the frame having an inflow edge, an outflow edge and a longitudinal axis, the frame comprising at least first, second, third and fourth sets of struts, and a plurality of coupling elements at the outflow edge of the frame,
wherein struts of the first set of struts are connected to adjacent struts of the first set of struts at a first plurality of nodes at the inflow edge,
wherein the first and second sets of struts are connected at a second plurality of nodes to define a first row of expandable cells,
wherein the second and third sets of struts are connected at a third plurality of nodes to define a second row of expandable cells, and
wherein the third and fourth sets of struts are connected at a fourth plurality of nodes to define a third row of expandable cells,
wherein in an original manufactured condition, struts axially aligned in a column with a coupling element of the plurality of coupling elements are configured to be less stiff than struts not axially aligned with the coupling element, and
wherein a length, width, or thickness of nodes connecting the struts axially aligned in the column with the coupling element are smaller than a respective length, width, or thickness of nodes connecting the struts that are not axially aligned with the coupling element.
12. The prosthesis of claim 11 , further comprising:
a valve body coupled to the frame.