IP Library Granted Patent US 8,888,712
Granted Patent B2
US 8,888,712 · App. 13/741,085 · Granted Nov 18, 2014

Tinnitus testing device and method

Inventors: Jeremy Turner (Jacksonville, IL); James Michael Kinder (Julian, CA)
Assignee: Board of Trustees of Southern Illinois University
A61B5/128A61B5/04845A61B5/121A61B5/04001A61F11/00
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Quick Facts
Patent No.
US 8,888,712
App. No.
13/741,085
Granted
Nov 18, 2014
Kind
B2
Abstract

Objectively identifying an acoustic characteristic of tinnitus of a subject. The subject is exposed to a sound pattern having a background acoustic signal preceding an audible silence. The background acoustic signal has a selected acoustic characteristic. An electrical response of the subject's central nervous system to the exposure to the sound pattern is measured. The measured electrical response has a first portion representing the electrical response of the subject's central nervous system to the background acoustic signal, and a second portion representing the electrical response of the subject's central nervous system to the audible silence in the sound pattern. The first portion of the measured electrical response is compared to the second portion of the measured electrical response and a determination is made as to whether the subject has tinnitus with an acoustic characteristic similar to the selected acoustic characteristic based on the comparison.

Claims (25)

1. A method for objectively identifying an acoustic characteristic of tinnitus of a human or animal subject comprising:

exposing the subject to a sound pattern having at least a first segment and a second segment via one or more transducers, wherein the sound pattern is continuous and has both a first acoustic characteristic and an audible silence during the first segment and has a second acoustic characteristic during the second segment, wherein the first acoustic characteristic during the first segment of the sound pattern has a first duration and the audible silence during the first segment of the sound pattern has a second duration, and wherein the first acoustic characteristic during the first segment of the sound pattern is different than the second acoustic characteristic during the second segment of the sound pattern;

measuring in an objective manner an electrical response of the subject's central nervous system to the exposure to the sound pattern via one or more electrodes, said measured electrical response having a first portion representing the electrical response of the subject's central nervous system to the exposure to the first acoustic characteristic and the audible silence during the first segment of the sound pattern, and said measured electrical response having a second portion representing the electrical response of the subject's central nervous system to the exposure to the second acoustic characteristic during the second segment of the sound pattern;

comparing, by the controller, the first portion of the measured electrical response to the second portion of the measured electrical response; and

determining, by the controller, whether the subject has tinnitus with an acoustic characteristic similar to the first acoustic characteristic based on said comparison.

2. The method of claim 1 wherein the first acoustic characteristic of the first segment of the sound pattern is a decibel level having a first value, and the second acoustic characteristic of the second segment of the sound pattern is a decibel level having a second value, wherein the second value is less than the first value.

3. The method of claim 1 wherein the sound pattern includes a third segment having a third acoustic characteristic, wherein the third acoustic characteristic is substantially the same as the first acoustic characteristic.

4. The method of claim 1 wherein measuring an electrical response of the subject's central nervous system to the exposure to the sound pattern comprises detecting electrical potentials evoked by the subject's central nervous system in response to the exposure to the sound pattern.

5. The method of claim 1 wherein measuring an electrical response of the subject's central nervous system to the exposure to the sound pattern comprises detecting electrical potentials evoked by the subject's central nervous system in response to the exposure to the sound pattern.

6. The method of claim 1 wherein the second segment has a shorter duration than the first segment and the audible silence includes removing or lowering the first acoustic characteristic.

7. The method of claim 1 wherein comparing the first portion of the measured electrical response to the second portion of the measured electrical response comprises analyzing a ratio between a signal characteristic of the first portion of the measured electrical response and a corresponding signal characteristic of the second portion of the measured electrical response.

8. The method of claim 1 wherein comparing the first portion of the measured electrical response to the second portion of the measured electrical response comprises analyzing a relationship between an amplitude of the first portion of the measured electrical response and an amplitude of the second portion of the measured electrical response.

9. A method for objectively identifying an acoustic characteristic of tinnitus of a human or animal subject comprising:

exposing the subject to a plurality of sound patterns via one or more transducers, each sound pattern of the plurality of sound patterns having at least a first segment and a second segment, wherein each sound pattern has a first acoustic characteristic having a first duration and an audible silence having a second duration during the first segment and has a second acoustic characteristic during the second segment, wherein the first acoustic characteristic is different than the second acoustic characteristic;

objectively measuring a plurality of electrical responses of the subject's central nervous system to the exposure to the plurality of sound patterns via one or more electrodes, wherein each of the plurality of measured electrical responses represents an electrical response of the subject's central nervous system to the exposure to a particular sound pattern of the plurality of sound patterns, and each measured electrical response has a first portion representing the electrical response of the subject's central nervous system to the exposure to the first segment of the particular sound pattern, and each measured electrical response has a second portion representing the electrical response of the subject's central nervous system to the exposure to the second segment of the particular sound pattern;

averaging, by the controller, the plurality of measured electrical responses together to produce an average measured electrical response signal of the subject's central nervous system to the exposure to the plurality of sound patterns, wherein the average measured electrical response signal has a first portion representing the average electrical response of the subject's central nervous system to the exposure to the first segments of the plurality of sound patterns, and wherein the average measured electrical response signal has a second portion representing the average electrical response of the subject's central nervous system to the exposure to the second segments of the plurality of sound patterns;

comparing, by the controller, a signal characteristic of the first portion of the average measured electrical response signal to a corresponding signal characteristic of the second portion of the average measured electrical response signal; and

determining, by the controller, whether the subject has tinnitus with an acoustic characteristic similar to the first acoustic characteristic based on said comparison.

10. The method of claim 9 wherein the first acoustic characteristic of the first segment of each sound pattern is a decibel level having a first value, and the second acoustic characteristic of the second segment of each sound pattern is a decibel level having a second value, wherein the second value is less than the first value.

11. The method of claim 9 wherein each sound pattern includes a third segment having a third acoustic characteristic, wherein the third acoustic characteristic is substantially the same as the first acoustic characteristic.

12. The method of claim 9 wherein measuring a plurality of electrical responses of the subject's central nervous system to the exposure to the plurality of sound patterns comprises detecting electrical potentials evoked by the subject's brain in response to the exposure to each of the plurality of sound patterns.

13. The method of claim 9 wherein measuring a plurality of electrical responses of the subject's central nervous system to the exposure to the plurality of sound patterns comprises detecting electrical potentials evoked by the subject's brain in response to the exposure to each of the plurality of sound patterns.

14. The method of claim 9 wherein the second segment of each sound pattern has a shorter duration than the first segment of each sound pattern and the audible silence during the first segment of each sound pattern includes removing or lowering the first acoustic characteristic of each sound pattern.

15. The method of claim 9 wherein each sound pattern of the plurality of sound patterns is uninterrupted between the at least first segment and the at least second segment, wherein the first duration of the first acoustic characteristic is separate from the second duration of the audible silence.

16. The method of claim 9 wherein comparing a signal characteristic of the first portion of the average measured electrical response signal to a corresponding signal characteristic of the second portion of the average measured electrical response signal comprises analyzing a ratio between an amplitude of the first portion of the average measured electrical response signal and an amplitude of the second portion of the average measured electrical response signal.

Assignments (2)
CONFIRMATORY LICENSE Recorded Mar 14, 2016
From: SOUTHERN ILLINOIS UNIVERSITY SCH OF MED
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 038081/0613 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 17, 2013
From: TURNER, JEREMY; KINDER, JAMES MICHAEL
To: BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY
Reel/Frame 030232/0212 →
Continuity (5)
Continuation 12397277 · Mar 3, 2009
Continuation In Part 11669767 · Jan 31, 2007
Provisional Application 60835162 · Aug 2, 2006
Provisional Application 60801229 · May 16, 2006
Related Publication 20130131543A1 · May 23, 2013