IP Library Granted Patent US 9,770,186
Granted Patent B2
US 9,770,186 · App. 13/769,917 · Granted Sep 26, 2017

Systems and methods for magnetic resonance imaging

Inventors: Eun-Kee Jeong (North Salt Lake, UT); Dennis L Parker (Centerville, UT); Kim Seong-Eun Choi (Salt Lake City, UT); Evgueni G Kholmovski (Salt Lake City, UT)
Assignee: National Institutes of Health (NIH), U.S. Dept. of Health and Human Services (DHHS), The United States of America NIH Division of Extramural Inventions and Technology Resources (DEITR)
A61B5/055G01R33/5615G01R33/5616G01R33/5676G01R33/56341G01R33/56509G01R33/56536G01R33/4806
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 9,770,186
App. No.
13/769,917
Granted
Sep 26, 2017
Kind
B2
Abstract

Methods and apparatus for operating an MRI system is provided. The disclosure provides a diffusion-prepared driven-equilibrium preparation for an imaging volume and acquiring 3-dimensional k-space data from said prepared volume by a plurality of echoplanar readouts of stimulated echoes. An excitation radio-frequency signal and first and second inversion RF signals are provided to define a field-of-view (FOV).

Claims (26)

1. A method for interleaved MR imaging, comprising:

performing a preparation sequence comprising:

providing an excitation radio-frequency (RF) signal;

immediately after said excitation RF signal, providing first and second inversion RF signals to define a field-of-view (FOV);

following the preparation sequence, performing an interleaved multi-slice acquisition of the FOV over a sequence of acquisition segments to acquire k-space data, wherein (i) each segment applies an imaging RF pulse to the FOV with a flip angle and (ii) the flip angle is increased over the sequence of the acquisition segments; and

reconstructing one or more images based on the k-space data.

2. The method of claim 1 , wherein said first and second inversion RF signals comprise first and second inversion RF pulses.

3. The method of claim 2 , wherein said first inversion RF pulse is applied immediately after said excitation RF signal.

4. The method of claim 2 , wherein said first and second inversion RF pulses are separated by a time approximately 5 ms or larger.

5. The method of claim 2 , wherein said first and second inversion RF pulses are separated by a time less than 5 ms.

6. The method of claim 2 , wherein said first and second inversion RF pulses are separated by a time more than 5 ms.

7. The method of claim 2 , further comprising providing slice-selective gradients that are selected such that magnetization within said FOV is preserved while magnetization external to said FOV is suppressed, thereby allowing magnetization in each of a plurality of slices to be maintained in its equilibrium state while exciting and imaging one or more others of said plurality of slices.

8. A system for interleaved magnetic resonance imaging (MRI), comprising:

an MRI scanner;

one or more computers configured to generate one or more instructions for:

performing a preparation sequence via the MRI scanner comprising:

providing an excitation radio-frequency (RF) signal;

immediately after said excitation RF signal, providing first and second inversion RF signals to define a field-of-view (FOV); and

following the preparation sequence, performing an interleaved multi-slice acquisition of the FOV via the MRI scanner over a sequence of acquisition segments to acquire k-space data, wherein (i) each segment applies an imaging RF pulse to the FOV with a flip angle and (ii) the flip angle is increased over the sequence of the acquisition segments; and

reconstructing one or more images based on the k-space data.

9. The system of claim 8 , wherein said first and second inversion RF signals comprise first and second inversion RF pulses.

10. The system of claim 9 , wherein said first inversion RF pulse is applied immediately after said excitation RF signal.

11. The system of claim 9 , wherein said first and second inversion RF pulses are separated by a time approximately 5 ms or larger.

12. The system of claim 9 , wherein said first and second inversion RF pulses are separated by a time less than 5 ms.

13. The system of claim 9 , wherein said first and second inversion RF pulses are separated by a time more than 5 ms.

14. The system of claim 9 , wherein said one or more instructions further includes an instruction for providing slice-selective gradients that are selected such that magnetization within said FOV is preserved while magnetization external to said FOV is suppressed, thereby allowing magnetization in each of a plurality of slices to be maintained in its equilibrium state while exciting and imaging one or more others of said plurality of slices.

Assignments (1)
CONFIRMATORY LICENSE Recorded Dec 23, 2016
From: UNIVERSITY OF UTAH
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 041187/0330 →
Continuity (3)
Division 11732382 · Apr 2, 2007
Provisional Application 60788533 · Mar 31, 2006
Related Publication 20130158384A1 · Jun 20, 2013