Compounds and uses thereof for treating inflammation and modulating immune responses
The present invention provides compounds, and compositions comprising these compounds, which have immunomodulatory activity and/or anti-inflammatory activity.
1. A method for reducing inflammation, wherein said method comprises administering to a subject in need thereof, 50-75 μg/ml of compound A2
2. The method, according to claim 1 , wherein TNF-α activity is inhibited.
3. The method, according to claim 1 , wherein the subject has inflammation associated with infection, an environmental toxin, an autoimmune condition, cardiovascular disease, intestinal inflammation, allergy, graft rejection, pathological immune cell proliferation or activity, and/or respiratory inflammation.
4. The method, according to claim 1 , wherein the subject has inflammation associated with rheumatoid arthritis, psoriasis, cardiovascular disease, inflammatory bowel disorder, septic shock and graft rejection.
5. The method, according to claim 1 , wherein the subject is a human.