IP Library Granted Patent US 9,127,036
Granted Patent B2
US 9,127,036 · App. 13/816,470 · Granted Sep 8, 2015

Synthetic bile acid compositions and methods

Inventors: Robert M. Moriarty (Michiana Shores, IN); Nathaniel E. David (Los Angeles, CA); Nadir Ahmeduddin Mahmood (Calabasas, CA)
Assignee: KYTHERA BIOPHARMACEUTICALS, INC.
C07J9/005A61K31/191Y10T436/201666
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Quick Facts
Patent No.
US 9,127,036
App. No.
13/816,470
Granted
Sep 8, 2015
Kind
B2
Abstract

Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.

Claims (4)

1. A compound that is deoxycholic acid (DCA) or a pharmaceutically acceptable salt thereof:

wherein said DCA has a 14 C content of less than 0.86 ppt.

2. A compound that is deoxycholic acid (DCA) or a pharmaceutically acceptable salt thereof:

wherein said DCA has a 14 C content of greater than 1 ppt.

Assignments (3)
MERGER AND CHANGE OF NAME Recorded Oct 10, 2019
From: KYTHERA BIOPHARMACEUTICALS, LLC; ALLERGAN SALES, LLC
To: ALLERGAN SALES, LLC
Reel/Frame 050684/0903 →
CHANGE OF NAME Recorded Oct 7, 2019
From: KYTHERA BIOPHARMACEUTICALS, INC.
To: KYTHERA BIOPHARMACEUTICALS, LLC
Reel/Frame 050648/0991 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 2, 2013
From: MORIARTY, ROBERT M.; DAVID, NATHANIEL E.; MAHMOOD, NADIR AHMEDUDDIN
To: KYTHERA BIOPHARMACEUTICALS, INC.
Reel/Frame 030731/0663 →
Continuity (1)
Related Publication 20130252931A1 · Sep 26, 2013