IP Library › Patent Application 13817763
Patent Application
App. No. 13/817,763

METHOD AND COMPOSITION FOR THE TREATMENT, PREVENTION, AND DIAGNOSIS OF CANCER CONTAINING OR DERIVED FROM CANCER STEM CELLS

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Quick Facts
Patent No.
US None
App. No.
13/817,763
Abstract

The invention provides a method and composition for the treatment, prevention, and diagnosis of cancer containing or derived from cancer stem cells.

Claims (5)

1 . A pharmaceutical composition comprising an RPN2 inhibitor for the treatment or prevention of cancer containing or derived from cancer stem cells.

2 . The pharmaceutical composition according to claim 1 , wherein the cancer stem cells carry a mutated p53 gene.

3 . The pharmaceutical composition according to claim 1 or 2 , wherein the RPN2 inhibitor is an siRNA against the RPN2 gene.

4 . A method for detecting cancer stem cells, comprising determining the presence or level of RPN2 expression.

5 . The method according to claim 4 , further comprising detecting a mutated p53 gene.

Assignments (2)
CHANGE OF NAME Recorded May 17, 2016
From: NATIONAL CANCER CENTER RESEARCH INSTITUTE
To: NATIONAL CANCER CENTER
Reel/Frame 039165/0040 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 20, 2013
From: OCHIYA, TAKAHIRO
To: NATIONAL CANCER CENTER RESEARCH INSTITUTE; 3-D MATRIX, LTD.
Reel/Frame 029838/0505 →