Granted Patent
B2
US 9,624,213 · App. 13/820,734 · Granted Apr 18, 2017
Compounds and methods for kinase modulation, and indications therefor
Inventors:
Prabha Ibrahim (Mountain View, CA); Chao Zhang (Moraga, CA); Wayne Spevak (Berkeley, CA); Jiazhong Zhang (Foster City, CA); Guoxian Wu (Palo Alto, CA); Jack Lin (Hercules, CA); Hanna Cho (Vernon Hills, IL); Marika Nespi (Berkeley, CA); Songyuan Shi (San Diego, CA); Todd Ewing (Walnut Creek, CA); Ying Zhang (Fremont, CA)
Assignee:
Plexxikon Inc.
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Abstract
Compounds active on protein kinases are described, as well as methods of making and using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.
Claims (5)
1. A compound of formula:
or a pharmaceutically acceptable salt, a hydrate, a solvate, a tautomer, or a stereoisomer thereof.
2. A compound which is:
3. A pharmaceutical composition comprising the compound of claim 1 or a pharmaceutically acceptable salt, a hydrate, a solvate, a tautomer, or a stereoisomer thereof, and a pharmaceutically acceptable excipient or carrier.
4. A pharmaceutical composition comprising the compound of claim 2 and a pharmaceutically acceptable excipient or carrier.
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Oct 22, 2013
From: IBRAHIM, PRABHA N.; ZHANG, CHAO; SPEVAK, WAYNE; ZHANG, JIAZHONG; WU, GUOXIAN; LIN, JACK; CHO, HANNO; NESPI, MARIKA; SHI, SONGYUAN; EWING, TODD; ZHANG, YING
To: PLEXXIKON INC.
Reel/Frame 031453/0880 →
Continuity (2)
Provisional Application
61440339
· Feb 7, 2011